Plants in anticancer drug discovery: from molecular mechanism to chemoprevention

AJ Siddiqui, S Jahan, R Singh, J Saxena… - BioMed Research …, 2022 - Wiley Online Library
Cancer is one of the primary causes of mortality globally, and the discovery of new
anticancer drugs is the most important need in recent times. Natural products have been …

Melatonin in cancer treatment: current knowledge and future opportunities

WH Talib, AR Alsayed, A Abuawad, S Daoud… - Molecules, 2021 - mdpi.com
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …

Metal/metal oxide nanoparticles: A revolution in the biosynthesis and medical applications

RA de Jesus, GC de Assis, RJ de Oliveira… - Nano-Structures & Nano …, 2024 - Elsevier
Nanoparticles with their various physical and chemical properties are commonly applied in
the environmental remediation systems, as well as in the field of biomedicine. We report the …

Combination anticancer therapies using selected phytochemicals

WH Talib, D Awajan, RA Hamed, AO Azzam… - Molecules, 2022 - mdpi.com
Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

Recent progress and future perspectives for zero agriculture waste technologies: Pineapple waste as a case study

PK Sarangi, AK Singh, RK Srivastava, VK Gupta - Sustainability, 2023 - mdpi.com
Worldwide, a huge production of agro-industrial wastes is observed every year in the milling,
brewing, agricultural, and food industries. Biochemical and bioactive substances can be …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Autophagy: Mechanisms and therapeutic potential of flavonoids in cancer

X Pang, X Zhang, Y Jiang, Q Su, Q Li, Z Li - Biomolecules, 2021 - mdpi.com
Autophagy, which is a conserved biological process and essential mechanism in
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …

Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts …

A Grabarska, P Wróblewska-Łuczka, W Kukula-Koch… - Molecules, 2021 - mdpi.com
Palmatine (PLT) is a natural isoquinoline alkaloid that belongs to the class of
protoberberines and exhibits a wide spectrum of pharmacological and biological properties …

[HTML][HTML] Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids

M Elbadawy, K Hayashi, H Ayame, Y Ishihara… - Biomedicine & …, 2021 - Elsevier
Despite its adverse effects, chemotherapy is generally used for the treatment of colorectal
cancer (CRC). Development of supplement preparations targeting cancer stem cells (CSCs) …

Restoring the immunity in the tumor microenvironment: Insights into immunogenic cell death in onco-therapies

ÁP Hernández, P Juanes-Velasco, A Landeira-Viñuela… - Cancers, 2021 - mdpi.com
Simple Summary Since the role of immune evasion was included as a hallmark in cancer,
the idea of cancer as a single cell mass that replicate unlimitedly in isolation was dissolved …