Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Plant antimicrobial peptides: structures, functions, and applications

J Li, S Hu, W Jian, C Xie, X Yang - Botanical Studies, 2021 - Springer
Antimicrobial peptides (AMPs) are a class of short, usually positively charged polypeptides
that exist in humans, animals, and plants. Considering the increasing number of drug …

Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Message in a bubble: shuttling small RNAs and proteins between cells and interacting organisms using extracellular vesicles

Q Cai, B He, S Wang, S Fletcher, D Niu… - Annual review of …, 2021 - annualreviews.org
Communication between plant cells and interacting microorganisms requires the secretion
and uptake of functional molecules to and from the extracellular environment and is …

Plant antimicrobial peptides

R Nawrot, J Barylski, G Nowicki, J Broniarczyk… - Folia microbiologica, 2014 - Springer
Plant antimicrobial peptides (AMPs) are a component of barrier defense system of plants.
They have been isolated from roots, seeds, flowers, stems, and leaves of a wide variety of …

A fungal effector suppresses the nuclear export of AGO1–miRNA complex to promote infection in plants

C Zhu, JH Liu, JH Zhao, T Liu… - Proceedings of the …, 2022 - National Acad Sciences
Communication between interacting organisms via bioactive molecules is widespread in
nature and plays key roles in diverse biological processes. Small RNAs (sRNAs) can travel …

Antifungal drugs: New insights in research & development

AM Nicola, P Albuquerque, HC Paes… - Pharmacology & …, 2019 - Elsevier
The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

Antifungal plant defensins: mechanisms of action and production

K Vriens, BPA Cammue, K Thevissen - Molecules, 2014 - mdpi.com
Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …

Antifungal defensins and their role in plant defense

AF Lacerda, ÉAR Vasconcelos, PB Pelegrini… - Frontiers in …, 2014 - frontiersin.org
Since the beginning of the 90s lots of cationic plant, cysteine-rich antimicrobial peptides
(AMP) have been studied. However, only coined the term “plant defensin,” after comparison …

Diversity of insect antimicrobial peptides and proteins-A functional perspective: A review

I Eleftherianos, W Zhang, C Heryanto… - International Journal of …, 2021 - Elsevier
The innate immune response of insects provides a robust line of defense against pathogenic
microbes and eukaryotic parasites. It consists of two types of overlapping immune …