Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3)

ZA Fayad, FK Swirski, C Calcagno, CS Robbins… - Journal of the American …, 2018 - jacc.org
It has long been recognized that the bone marrow is the primary site of origin for circulating
monocytes that may later become macrophages in atherosclerotic lesions. However, only in …

Emerging magnetic resonance imaging techniques for atherosclerosis imaging: high magnetic field, relaxation time mapping, and fluorine-19 imaging

RCI Wüst, C Calcagno, MRR Daal… - … , and vascular biology, 2019 - Am Heart Assoc
Atherosclerosis is a prevalent disease affecting a large portion of the population at one point
in their lives. There is an unmet need for noninvasive diagnostics to identify and characterize …

Low‐intensity focused ultrasound‐responsive ferrite‐encapsulated nanoparticles for atherosclerotic plaque neovascularization theranostics

J Yao, Z Yang, L Huang, C Yang, J Wang… - Advanced …, 2021 - Wiley Online Library
Pathological angiogenesis is a crucial factor that causes atherosclerotic plaque rupture.
Sinoporphyrin sodium‐mediated sonodynamic therapy (DVDMS‐SDT) induces regression …

An intelligent T 1–T 2 switchable MRI contrast agent for the non-invasive identification of vulnerable atherosclerotic plaques

C Pan, J Lin, J Zheng, C Liu, B Yuan, OU Akakuru… - Nanoscale, 2021 - pubs.rsc.org
Unlike stable atherosclerotic plaques, vulnerable plaques are very likely to cause serious
cardio-cerebrovascular diseases. Meanwhile, how to non-invasively identify vulnerable …

Leukotriene A4 hydrolase inhibition improves age-related cognitive decline via modulation of synaptic function

JM Adams, SV Rege, AT Liu, NV Vu, S Raina… - Science …, 2023 - science.org
Leukotrienes, a class of inflammatory bioactive lipids, are well studied in the periphery, but
less is known of their importance in the brain. We identified that the enzyme leukotriene A4 …

Osteopontin targeted non-invasive nanoprobes with amplified surface plasmon resonance for photothermally enhanced multimodal precision imaging of vulnerable …

S Wang, X Zhang, Y Liu, Y Wang, N Sun, J Yin… - Chemical Engineering …, 2023 - Elsevier
Effective strategies for accurate differentiation of the vulnerable atherosclerosis (AS) plaques
at molecular level for clinical diagnosis have yet been developed. Herein, a versatile S …

Ferrite-encapsulated nanoparticles with stable photothermal performance for multimodal imaging-guided atherosclerotic plaque neovascularization therapy

Z Yang, J Yao, J Wang, C Zhang, Y Cao, L Hao… - Biomaterials …, 2021 - pubs.rsc.org
Pathological angiogenesis is a critical contributor to atherosclerotic plaque rupture.
However, there are few effective theranostic strategies to stabilize plaques by suppressing …

[HTML][HTML] Research methods for animal models of atherosclerosis

Y Zhang, M Fatima, S Hou, L Bai… - Molecular medicine …, 2021 - spandidos-publications.com
Atherosclerosis is a chronic inflammatory disease that threatens human health and lives by
causing vascular stenosis and plaque rupture. Various animal models have been employed …

Evolving role of PET in detecting and characterizing atherosclerosis

PF Høilund-Carlsen, MC Moghbel, O Gerke, A Alavi - PET clinics, 2019 - pet.theclinics.com
Evolving Role of PET in Detecting and Characterizing Atherosclerosis - PET Clinics Skip to
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Emerging Roles and Therapeutic Applications of Arachidonic Acid Pathways in Cardiometabolic Diseases

Y Hu, W Li, X Cheng, H Yang, ZG She, J Cai… - Circulation …, 2024 - Am Heart Assoc
Cardiometabolic disease has become a major health burden worldwide, with sharply
increasing prevalence but highly limited therapeutic interventions. Emerging evidence has …