The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Y Cao, F Jian, J Wang, Y Yu, W Song, A Yisimayi… - Nature, 2023 - nature.com
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …

Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa

H Tegally, M Moir, J Everatt, M Giovanetti… - Nature medicine, 2022 - nature.com
Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …

[HTML][HTML] BA. 2.12. 1, BA. 4 and BA. 5 escape antibodies elicited by Omicron infection

Y Cao, A Yisimayi, F Jian, W Song, T Xiao, L Wang… - Nature, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage 1. The receptor …

Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a …

C Menni, AM Valdes, L Polidori, M Antonelli… - The Lancet, 2022 - thelancet.com
Summary Background The SARS-CoV-2 variant of concern, omicron, appears to be less
severe than delta. We aim to quantify the differences in symptom prevalence, risk of hospital …

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

A Yisimayi, W Song, J Wang, F Jian, Y Yu, X Chen… - Nature, 2024 - nature.com
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

SSA Karim, QA Karim - The lancet, 2021 - thelancet.com
SARS-CoV-2 variant of concern (VoC), omicron, 2 was reported. Omicron emerged in a
COVID-19-weary world in which anger and frustration with the pandemic are rife amid …

Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …