Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …

Economics and mental health are intertwined. Apart from the accumulating evidence of the
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …

Individuals with disorders that include psychotic symptoms (ie psychotic disorders)
experience broad cognitive impairments in the chronic state, indicating a dimension of …

Abstract The 22q11. 2 deletion syndrome (22q11DS) is associated with a 20–25% risk of
schizophrenia. In a cohort of 962 individuals with 22q11DS, we examined the shared …

Cognitive dysfunction is a well-established feature of schizophrenia, and there is evidence
suggesting that cognitive deficits are secondary to abnormal neurodevelopment leading to …

Objective: Schizophrenia is associated with a marked cognitive impairment that is widely
believed to remain stable after illness onset. Yet, to date, 10-year prospective studies of …

Importance Neurocognition is a central characteristic of schizophrenia and other psychotic
disorders. Identifying the pattern and severity of neurocognitive functioning during the “near …

Cognitive impairment is a core feature of schizophrenia and a major contributor to poor
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …