Ribosomal proteins have important roles in maintaining the structure and function of mature
ribosomes, but they also drive crucial rearrangement reactions during ribosome biogenesis …

Ribosomes translate mRNA into proteins and are essential for every living organism. In
eukaryotes, both ribosomal subunits are rapidly assembled in a strict hierarchical order …

The dysregulation of ribosome biogenesis is a hallmark of cancer, facilitating the adaptation
to altered translational demands essential for various aspects of tumor progression. This …

Ribosome biogenesis (RB) is a highly conserved process across eukaryotes that results in
the assembly of functional ribosomal subunits. Studies in Saccharomyces cerevisiae and …

Ribosome biogenesis is a highly regulated cellular process requiring a large cohort of
accessory factors to ensure the accurate production of ribosomes. Dysregulation of …

Ribosome biogenesis is essential for cell growth, proliferation, and animal development. Its
deregulation leads to various human disorders such as ribosomopathies and cancer. Thus …

Cancer cells frequently upregulate ribosome production to support tumorigenesis. While
small nucleolar RNAs (snoRNAs) are critical for ribosome biogenesis, the roles of other …

Biomolecular condensates are key features of intracellular compartmentalization. As the
most prominent nuclear condensate in eukaryotes, the nucleolus is a layered multiphase …

The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the
focus of advanced microscopic approaches. Recently, it has been possible to identify and …

Eukaryotic ribosome assembly is an intricate process that involves four ribosomal RNAs, 80
ribosomal proteins, and over 200 biogenesis factors that take part in numerous …