Cortico-striatal-thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment

SK Peters, K Dunlop, J Downar - Frontiers in systems neuroscience, 2016 - frontiersin.org
The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …

Structural and functional imaging markers for susceptibility to psychosis

C Andreou, S Borgwardt - Molecular psychiatry, 2020 - nature.com
The introduction of clinical criteria for the operationalization of psychosis high risk provided a
basis for early detection and treatment of vulnerable individuals. However, about two-thirds …

Structural and diffusion MRI based schizophrenia classification using 2D pretrained and 3D naive Convolutional Neural Networks

M Hu, X Qian, S Liu, AJ Koh, K Sim, X Jiang… - Schizophrenia …, 2022 - Elsevier
The ability of automatic feature learning makes Convolutional Neural Network (CNN)
potentially suitable to uncover the complex and widespread brain changes in schizophrenia …

[HTML][HTML] Updating and characterizing neuroanatomical markers in high-risk subjects, recently diagnosed and chronic patients with schizophrenia: A revised coordinate …

D Liloia, C Brasso, F Cauda, L Mancuso, A Nani… - Neuroscience & …, 2021 - Elsevier
Characterizing neuroanatomical markers of different stages of schizophrenia (SZ) to assess
pathophysiological models of how the disorder develops is an important target for the …

Functional brain network dysfunctions in subjects at high-risk for psychosis: a meta-analysis of resting-state functional connectivity

L Del Fabro, A Schmidt, L Fortea, G Delvecchio… - Neuroscience & …, 2021 - Elsevier
Although emerging evidence suggests that altered functional connectivity (FC) of large-scale
neural networks is associated with disturbances in individuals at high-risk for psychosis, the …

[HTML][HTML] Mesolimbic dopamine function is related to salience network connectivity: an integrative positron emission tomography and magnetic resonance study

RA McCutcheon, MM Nour, T Dahoun, S Jauhar… - Biological …, 2019 - Elsevier
Background A wide range of neuropsychiatric disorders, from schizophrenia to drug
addiction, involve abnormalities in both the mesolimbic dopamine system and the cortical …

Advances in microstructural diffusion neuroimaging for psychiatric disorders

O Pasternak, S Kelly, VJ Sydnor, ME Shenton - Neuroimage, 2018 - Elsevier
Understanding the neuropathological underpinnings of mental disorders such as
schizophrenia, major depression, and bipolar disorder is an essential step towards the …

Insula functional connectivity in schizophrenia: subregions, gradients, and symptoms

Y Tian, A Zalesky, C Bousman, I Everall… - Biological Psychiatry …, 2019 - Elsevier
Background The insular cortex is connected to a diverse network of cortical and subcortical
areas. This study aimed to investigate whether the diversity in functional connectivity across …

Salience network connectivity in the insula is associated with individual differences in interoceptive accuracy

JSX Chong, GJP Ng, SC Lee, J Zhou - Brain Structure and Function, 2017 - Springer
The insula and the anterior cingulate cortex are core brain regions that anchor the salience
network, one of several large-scale intrinsic functional connectivity networks that have been …

Cannabidiol attenuates insular dysfunction during motivational salience processing in subjects at clinical high risk for psychosis

R Wilson, MG Bossong, E Appiah-Kusi, N Petros… - Translational …, 2019 - nature.com
Accumulating evidence points towards the antipsychotic potential of cannabidiol. However,
the neurocognitive mechanisms underlying the antipsychotic effect of cannabidiol remain …