SARS-CoV-2: pathogenesis, therapeutics, variants, and vaccines

X Li, Z Mi, Z Liu, P Rong - Frontiers in Microbiology, 2024 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), emerged in December 2019 with staggering economic fallout …

Focusing on the cytokine storm in the battle against COVID-19: the rising role of mesenchymal-derived stem cells

A Naeem, A Waseem, AJ Siddiqui, B Ray, R Sinha… - Stem Cells, 2024 - Elsevier
A worldwide pandemic known as coronavirus disease-19 (COVID-19) has caused various
clinical complications, ranging from carriers without symptoms to acute respiratory distress …

[HTML][HTML] Nimotuzumab Increases the Recovery Rate of Severe and Critical COVID-19 Patients: Evaluation in the Real-World Scenario

H Diaz, J Jiménez, A Hernández, L Valdés… - Frontiers in public …, 2022 - frontiersin.org
EGFR signaling is an important regulator of SARS-CoV induced lung damage, inflammation
and fibrosis. Nimotuzumab is a humanized anti-EGFR antibody registered for several cancer …

[HTML][HTML] Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells

N Numao, S Kawaguchi, J Ding, T Karasawa… - Immunologic …, 2022 - Springer
Upon viral infection, dysregulated immune responses are associated with the disease
exacerbation and poor prognosis. The Janus kinase/signal transducers and activators of …

[HTML][HTML] SARS-CoV-2 associated immune dysregulation and COVID-associated pulmonary aspergilliosis (CAPA): A Cautionary Tale

DA Worku - International Journal of Molecular Sciences, 2022 - mdpi.com
As the global SARS-CoV-2 pandemic continues to plague healthcare systems, it has
become clear that opportunistic pathogens cause a considerable proportion of SARS-CoV-2 …

[PDF][PDF] SARS-CoV-2-Spike Interactions with the Renin-Angiotensin-Aldosterone System-Consequences of Adverse Reactions of Vaccination

KJ Lehmann - Journal of Biology, 2023 - researchgate.net
Abstract The protective Angiotensin-Converting Enzyme 2 (ACE2)-essential part of the
Renin-Angiotensin-Aldosterone System (RAAS)-is the target receptor for its physiological …

[HTML][HTML] Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism

L Yu - Biology, 2023 - mdpi.com
The main purpose of this Special Issue is to provide readers with current understandings of
the interactions and causal relations among injury stimuli (including microorganism …

[HTML][HTML] Efficacy and safety of Ixekizumab vs. low-dose IL-2 vs. Colchicine vs. standard of care in the treatment of patients hospitalized with moderate-to-critical …

LP Bonifácio, E Ramacciotti, LB Agati… - Revista da Sociedade …, 2023 - SciELO Brasil
Background: Cases of coronavirus disease 2019 (COVID-19) requiring hospitalization
continue to appear in vulnerable populations, highlighting the importance of novel …

[HTML][HTML] Coronavirus disease update on epidemiology, virology, and prevention

S Banava, SA Gansky, MS Reddy - Compendium of continuing …, 2021 - ncbi.nlm.nih.gov
Abstract In March 2020, the World Health Organization declared COVID-19 as the first
coronavirus-initiated pandemic. COVID-19's fast-paced global spread with a broad range of …

Cytokine storm in COVID-19 and other diseases: emerging therapeutic interventions

S Sahu, R Dharra, M Gun, S Datta, AK Akela, A Kumar - Stem Cells, 2024 - Elsevier
COVID-19 has killed millions globally. SARS-CoV-2, a virus that belongs to the
Coronaviridae family, causes COVID-19. Literature suggests that COVID-19-related illness …