Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

DL Eizirik, L Pasquali, M Cnop - Nature Reviews Endocrinology, 2020 - nature.com
Loss of functional β-cell mass is the key mechanism leading to the two main forms of
diabetes mellitus—type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) …

[HTML][HTML] Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus

MP Nekoua, EK Alidjinou, D Hober - Nature Reviews Endocrinology, 2022 - nature.com
Enteroviruses are believed to trigger or accelerate islet autoimmunity in genetically
susceptible individuals, thereby resulting in loss of functional insulin-producing β-cells and …

[HTML][HTML] Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy

AVA Mariadoss, AS Sivakumar, CH Lee… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a collection of metabolic and pathophysiological disorders
manifested with high glucose levels in the blood due to the inability of β-pancreatic cells to …

[HTML][HTML] Mediterranean diet as an antioxidant: the impact on metabolic health and overall wellbeing

KV Gantenbein, C Kanaka-Gantenbein - Nutrients, 2021 - mdpi.com
It has been established, worldwide, that non-communicable diseases such as obesity,
diabetes, metabolic syndrome, and cardiovascular events account for a high percentage of …

[HTML][HTML] Functional and metabolic alterations of gut microbiota in children with new-onset type 1 diabetes

X Yuan, R Wang, B Han, CJ Sun, R Chen… - Nature …, 2022 - nature.com
Gut dysbiosis has been linked to type 1 diabetes (T1D); however, microbial capacity in T1D
remains unclear. Here, we integratively profiled gut microbial functional and metabolic …

Type 1 diabetes

T Quattrin, LD Mastrandrea, LSK Walker - The Lancet, 2023 - thelancet.com
Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …

[HTML][HTML] Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era

AAS Akil, E Yassin, A Al-Maraghi, E Aliyev… - Journal of translational …, 2021 - Springer
Type 1 diabetes affects millions of people globally and requires careful management to
avoid serious long-term complications, including heart and kidney disease, stroke, and loss …

The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases

A Andreadi, A Bellia, N Di Daniele, M Meloni… - Current opinion in …, 2022 - Elsevier
Abstract Type 2 Diabetes Mellitus (T2D) is a chronic disease with a pandemic incidence
whose pathogenesis has not yet been clarified. Raising evidence highlighted the role of …

Antibiotics in the pathogenesis of diabetes and inflammatory diseases of the gastrointestinal tract

AC Fenneman, M Weidner, LA Chen… - Nature Reviews …, 2023 - nature.com
Antibiotic use is increasing worldwide. However, the use of antibiotics is clearly associated
with changes in gut microbiome composition and function, and perturbations have been …

[HTML][HTML] Relevance of essential trace elements in nutrition and drinking water for human health and autoimmune disease risk

D Cannas, E Loi, M Serra, D Firinu, P Valera… - Nutrients, 2020 - mdpi.com
Trace elements produce double-edged effects on the lives of animals and particularly of
humans. On one hand, these elements represent potentially toxic agents; on the other hand …