[HTML][HTML] SARS-CoV-2 and the host cell: a tale of interactions

M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …

[HTML][HTML] Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

[HTML][HTML] Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study

MM Etter, TA Martins, L Kulsvehagen… - Nature …, 2022 - nature.com
Growing evidence links COVID-19 with acute and long-term neurological dysfunction.
However, the pathophysiological mechanisms resulting in central nervous system …

[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

[HTML][HTML] SARS-CoV-2 accessory proteins reveal distinct serological signatures in children

A Hachim, H Gu, O Kavian, M Mori, MYW Kwan… - Nature …, 2022 - nature.com
The antibody response magnitude and kinetics may impact clinical severity, serological
diagnosis and long-term protection of COVID-19, which may play a role in why children …

Viral mimicry of interleukin-17A by SARS-CoV-2 ORF8

X Wu, T Xia, WJ Shin, KM Yu, W Jung, A Herrmann… - MBio, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection triggers cytokine-
mediated inflammation, leading to a myriad of clinical presentations in COVID-19. The SARS …

[HTML][HTML] The tryptophan catabolite or kynurenine pathway in COVID-19 and critical COVID-19: a systematic review and meta-analysis

AF Almulla, T Supasitthumrong… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is accompanied by activated
immune-inflammatory pathways and oxidative stress, which both induce indoleamine-2, 3 …

[HTML][HTML] Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

[HTML][HTML] Differential roles of regulatory T cells in acute respiratory infections

M Jovisic, N Mambetsariev, BD Singer… - The Journal of …, 2023 - Am Soc Clin Investig
JCI - Differential roles of regulatory T cells in acute respiratory infections Go to JCI Insight About
Editors Consulting Editors For authors Publication ethics Alerts Advertising Job board Subscribe …

[HTML][HTML] NSP4 and ORF9b of SARS-CoV-2 induce pro-inflammatory mitochondrial DNA release in inner membrane-derived vesicles

MI Faizan, R Chaudhuri, S Sagar, S Albogami… - Cells, 2022 - mdpi.com
Circulating cell-free mitochondrial DNA (cf-mtDNA) has been found in the plasma of
severely ill COVID-19 patients and is now known as a strong predictor of mortality. However …