Effect of continuous renal replacement therapy with the oxiris hemofilter on critically ill patients: a narrative review

Y Li, P Sun, K Chang, M Yang, N Deng… - Journal of Clinical …, 2022 - mdpi.com
Critically ill patients with sepsis and severe COVID-19 are commonly characterized by a
dysregulated immune response and an acute kidney injury. Continuous renal replacement …

Current understanding of the innate control of toll-like receptors in response to SARS-CoV-2 infection

HE Jung, HK Lee - Viruses, 2021 - mdpi.com
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, threatens the entire world. It …

[HTML][HTML] Rhein: A novel antibacterial compound against Streptococcus mutans infection

V Folliero, F Dell'Annunziata, E Roscetto… - Microbiological …, 2022 - Elsevier
Streptococcus mutans (S. mutans) is considered the main causative agent of dental caries.
The study aims to evaluate the antimicrobial activity of a natural plant product, pure 4, 5'' …

An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications

LJ Shih, CC Yang, MT Liao, KC Lu, WC Hu, CP Lin - Virulence, 2023 - Taylor & Francis
The global coronavirus disease 2019 (COVID-19) pandemic has a detrimental impact on
public health. COVID-19 usually manifests as pneumonia, which can progress into acute …

Low-molecular-weight synthetic antioxidants: classification, pharmacological profile, effectiveness and trends

M Stoia, S Oancea - Antioxidants, 2022 - mdpi.com
Mounting research has been performed and published on natural antioxidants, more so than
on synthetic ones, as key molecules that control oxidative damage and its pathway to …

Treatment with quercetin inhibits SARS-CoV-2 N protein-induced acute kidney injury by blocking Smad3-dependent G1 cell-cycle arrest

W Wu, W Wang, L Liang, J Chen, B Wei, XR Huang… - Molecular Therapy, 2023 - cell.com
Increasing evidence shows that SARS-CoV-2 can infect kidneys and cause acute kidney
injury (AKI) in critically ill COVID-19 patients. However, mechanisms through which COVID …

[PDF][PDF] Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia

IV Aramburu, D Hoving, SI Vernardis, MCF Tin… - Immunity, 2022 - cell.com
The factors that influence survival during severe infection are unclear. Extracellular
chromatin drives pathology, but the mechanisms enabling its accumulation remain elusive …

Assessing humoral immuno-inflammatory pathways associated with respiratory failure in COVID-19 patients

M Regolo, A Sorce, M Vaccaro, M Colaci… - Journal of Clinical …, 2023 - mdpi.com
All severe cases of SARS-CoV-2 infections are characterized by a high risk of disease
progression towards ARDS, leading to a bad outcome. Respiratory symptoms in COVID-19 …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

The Dynamic Role of FOXP3+ Tregs and Their Potential Therapeutic Applications During SARS-CoV-2 Infection

Z Xu, X Jiang, X Dai, B Li - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has been raging all around the world since the
beginning of 2020, and leads to acute respiratory distress syndrome (ARDS) with strong …