Tripterin liposome relieves severe acute respiratory syndrome as a potent COVID-19 treatment

H Que, W Hong, T Lan, H Zeng, L Chen… - Signal transduction and …, 2022 - nature.com
Abstract For coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), 15–30% of patients are likely to develop COVID-19 …

Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19

X Li, Z Zhang, Z Wang… - Signal Transduction and …, 2022 - nature.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced …

A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19

L Xia, L Yuan, Y Hu, J Liu, G Hu, R Qi… - Cellular & Molecular …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is
closely associated with coronavirus disease 2019 (COVID-19) severity and lethality …

[HTML][HTML] Quantitative serum NMR spectroscopy stratifies COVID-19 patients and sheds light on interfaces of host metabolism and the immune response with cytokines …

T Rössler, G Berezhnoy, Y Singh, C Cannet… - Metabolites, 2022 - mdpi.com
The complex manifestations of COVID-19 are still not fully decoded on the molecular level.
We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum …

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets

M Li, M Wang, Y Wen, H Zhang, GN Zhao, Q Gao - MedComm, 2023 - Wiley Online Library
Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

The immunology of SARS-CoV-2 infection and vaccines in solid organ transplant recipients

D Dęborska-Materkowska, D Kamińska - Viruses, 2021 - mdpi.com
Since its outbreak in December 2019, the coronavirus disease 2019 (COVID-19) pandemic,
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to an …

The role of peroxisome proliferator-activated receptors in the modulation of hyperinflammation induced by SARS-CoV-2 infection: A perspective for COVID-19 therapy

A Hasankhani, A Bahrami, B Tavakoli-Far… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a severe respiratory disease caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the lower …

Tocilizumab, netakimab, and baricitinib in patients with mild-to-moderate COVID-19: An observational study

EA Bryushkova, VD Skatova, ZY Mutovina… - PloS one, 2022 - journals.plos.org
Objective The aim of the study was to assess inflammatory markers and clinical outcomes in
adult patients admitted to hospital with mild-to-moderate COVID-19 and treated with a …

Pathogenic pathways and therapeutic targets of inflammation in heart diseases: A focus on Interleukin‐1

MG Del Buono, A Bonaventura… - European Journal of …, 2024 - Wiley Online Library
Background An exuberant and dysregulated inflammatory response contributes to the
development and progression of cardiovascular diseases (CVDs). Methods This narrative …

Recent advances in aptasensor for cytokine detection: A review

J Kim, S Noh, JA Park, SC Park, SJ Park, JH Lee… - Sensors, 2021 - mdpi.com
Cytokines are proteins secreted by immune cells. They promote cell signal transduction and
are involved in cell replication, death, and recovery. Cytokines are immune modulators, but …