m6A-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with LUAD

F Xu, X Huang, Y Li, Y Chen, L Lin - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Lung adenocarcinoma (LUAD) is the most frequent subtype of lung cancer worldwide.
However, the survival rate of LUAD patients remains low. N6-methyladenosine (m 6 A) and …

Patterns of carbon-bound exogenous compounds impact disease pathophysiology in lung cancer subtypes in different ways

J Shen, N Sun, J Wang, P Zens, T Kunzke, A Buck… - ACS …, 2023 - ACS Publications
Carbon-bound exogenous compounds, such as polycyclic aromatic hydrocarbons (PAHs),
tobacco-specific nitrosamines, aromatic amines, and organohalogens, are known to affect …

Screening and validation of platelet activation-related lncRNAs as potential biomarkers for prognosis and immunotherapy in gastric cancer patients

M Yuan, Y Jia, Y Xing, Y Wang, Y Liu, X Liu… - Frontiers in …, 2022 - frontiersin.org
Background: Platelets (PLT) have a significant effect in promoting cancer progression and
hematogenous metastasis. However, the effect of platelet activation-related lncRNAs (PLT …

Prognostic model and immunotherapy prediction based on molecular chaperone-related lncRNAs in lung adenocarcinoma

Y Xu, T Tao, S Li, S Tan, H Liu, X Zhu - Frontiers in genetics, 2022 - frontiersin.org
Introduction: Molecular chaperones and long non-coding RNAs (lncRNAs) have been
confirmed to be closely related to the occurrence and development of tumors, especially …

m6A‐related lncRNAs as potential biomarkers and the lncRNA ELFN1‐AS1/miR‐182‐5p/BCL‐2 regulatory axis in diffuse large B‐cell lymphoma

Q Yang, Y Lu, A Du - Journal of Cellular and Molecular …, 2024 - Wiley Online Library
Diffuse large B‐cell lymphoma (DLBCL) is the most common lymphoid subtype. However,
unsatisfactory survival outcomes remain a major challenge, and the underlying mechanisms …

[HTML][HTML] Construction and validation of a novel angiogenesis pattern to predict prognosis and immunotherapy efficacy in colorectal cancer

Z Li, Y Liu, P Guo, Y Wei - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Evidence suggests that the tumor microenvironment (TME) affects the tumor
active response to immunotherapy. Tumor angiogenesis is closely related to the TME …

Integrated analysis reveals prognostic value and immune correlates of CD86 expression in lower grade glioma

H Qiu, W Tian, Y He, J Li, C He, Y Li, N Liu… - Frontiers in oncology, 2021 - frontiersin.org
Background CD86 has great potential to be a new target of immunotherapy by regulating
cancer immune response. However, it remains unclear whether CD86 is a friend or foe in …

SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo

Y Liu, X Fan, C Jiang, S Xu - Human Cell, 2023 - Springer
Enhancer of zeste homolog 2 (EZH2) is an important epigenetic regulator, and is associated
with the malignant progression of lung cancer. However, the mechanisms of EZH2 on lung …

Identification of prognostic values of the transcription factor-CpG-gene triplets in lung adenocarcinoma: A narrative review

D Lian, L Lian, D Zeng, M Zhang, M Chen, Y Liu… - Medicine, 2022 - journals.lww.com
Objective: Abnormal DNA methylation can regulate carcinogenesis in lung adenocarcinoma
(LUAD), while transcription factors (TFs) mediate methylation in a site-specific manner to …

Construction and validation of an angiogenesis-related lncRNA prognostic model in lung adenocarcinoma

Q Gong, X Huang, X Chen, L Zhang, C Zhou, S Li… - Frontiers in …, 2023 - frontiersin.org
Background: There is increasing evidence that long non-coding RNAs (lncRNAs) can be
used as potential prognostic factors for cancer. This study aimed to develop a prognostic …