Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
Review of therapeutic mechanisms and applications based on SARS-CoV-2 neutralizing antibodies
COVID-19 pandemic is a global public health emergency. Despite extensive research, there
are still few effective treatment options available today. Neutralizing-antibody-based …
are still few effective treatment options available today. Neutralizing-antibody-based …
SARS‐CoV‐2 neutralising antibody therapies: Recent advances and future challenges
The COVID‐19 pandemic represents an unparalleled global public health crisis. Despite
concerted research endeavours, the repertoire of effective treatment options remains limited …
concerted research endeavours, the repertoire of effective treatment options remains limited …
[HTML][HTML] A multi-center, adaptive, randomized, platform trial to evaluate the effect of repurposed medicines in outpatients with early coronavirus disease 2019 (COVID …
G Reis, EASM Silva, DCM Silva… - Gates Open …, 2021 - gatesopenresearch.org
Background: Although vaccines are currently available for coronavirus disease 2019
(COVID-19), there remains a need for an effective and affordable outpatient treatment for …
(COVID-19), there remains a need for an effective and affordable outpatient treatment for …
Research Progress on Spike-Dependent SARS-CoV-2 Fusion Inhibitors and Small Molecules Targeting the S2 Subunit of Spike
MR Freidel, RS Armen - Viruses, 2024 - mdpi.com
Since the beginning of the COVID-19 pandemic, extensive drug repurposing efforts have
sought to identify small-molecule antivirals with various mechanisms of action. Here, we aim …
sought to identify small-molecule antivirals with various mechanisms of action. Here, we aim …
[HTML][HTML] Computational screening of potential bromodomain-containing protein 2 inhibitors for blocking SARS-CoV-2 infection through pharmacophore modeling …
S Xu, H Yuan, L Li, K Yang, L Zhao - Arabian Journal of Chemistry, 2024 - Elsevier
Recently, human bromodomain-containing protein 2 (BRD2) has been reported as a
potential drug target in host cells to combat SARS-CoV-2 as well as to treat COVID-19. In …
potential drug target in host cells to combat SARS-CoV-2 as well as to treat COVID-19. In …
Construction of a Hantaan Virus Phage Antibody Library and Screening for Potential Neutralizing Activity
Z Li, H Zhang, X Yu, Y Zhang, L Chen - Viruses, 2023 - mdpi.com
China is one of the main epidemic areas for hemorrhagic fever with renal syndrome (HFRS).
Currently, there is no human antibody specific to Hantaan virus (HTNV) for the emergency …
Currently, there is no human antibody specific to Hantaan virus (HTNV) for the emergency …