Mechanisms of Aortic Dilation in Patients With Bicuspid Aortic Valve: JACC State-of-the-Art Review

JF Rodríguez-Palomares, L Dux-Santoy… - Journal of the American …, 2023 - jacc.org
Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Bicuspid aortic valve associated aortopathy: 2022 guideline update

R Verma, G Cohen, J Colbert… - Current Opinion in …, 2023 - journals.lww.com
BAV aortopathy is a common and heterogenous clinical problem. The decision making
around timing of intervention requires a personalized approach that is based on the aortic …

Machine learning for the automatic assessment of aortic rotational flow and wall shear stress from 4D flow cardiac magnetic resonance imaging

J Garrido-Oliver, J Aviles, MM Córdova… - European …, 2022 - Springer
Abstract Objective Three-dimensional (3D) time-resolved phase-contrast cardiac magnetic
resonance (4D flow CMR) allows for unparalleled quantification of blood velocity. Despite …

Blood–wall fluttering instability as a physiomarker of the progression of thoracic aortic aneurysms

TY Zhao, EMI Johnson, G Elisha, S Halder… - Nature Biomedical …, 2023 - nature.com
The diagnosis of aneurysms is informed by empirically tracking their size and growth rate.
Here, by analysing the growth of aortic aneurysms from first principles via linear stability …

Impact of extra-anatomical bypass on coarctation fluid dynamics using patient-specific lumped parameter and Lattice Boltzmann modeling

R Sadeghi, B Tomka, S Khodaei, MA Daeian… - Scientific Reports, 2022 - nature.com
Accurate hemodynamic analysis is not only crucial for successful diagnosis of coarctation of
the aorta (COA), but intervention decisions also rely on the hemodynamics assessment in …

Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics

S Khodaei, L Garber, J Bauer, A Emadi… - Scientific Reports, 2022 - nature.com
Transcatheter aortic valve replacement (TAVR) is a frequently used minimally invasive
intervention for patient with aortic stenosis across a broad risk spectrum. While coronary …

Wall shear stress angle is associated with aortic growth in bicuspid aortic valve patients

SCS Minderhoud, JW Roos-Hesselink… - European Heart …, 2022 - academic.oup.com
Aims Aortic wall shear stress (WSS) distributions in bicuspid aortic valve (BAV) patients have
been associated with aortic dilatation, but prospective, longitudinal data are missing. This …

Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention

P Garg, M Markl, J Sathananthan, SL Sellers… - Nature Reviews …, 2024 - nature.com
Aortic blood flow patterns are closely linked to the morphology and function of the left
ventricle, aortic valve and aorta. These flow patterns demonstrate the exceptional …

Hemodynamic assessment in bicuspid aortic valve disease and aortic dilation: new insights from voxel-by-voxel analysis of reverse flow, stasis, and energetics

P Geeraert, F Jamalidinan, F Burns, K Jarvis… - … in Bioengineering and …, 2022 - frontiersin.org
Objectives: Clinical management decisions surrounding ascending aorta (AAo) dilation in
bicuspid aortic valve (BAV) disease benefit from personalized predictive tools. 4D-flow MRI …

4D-flow MRI derived wall shear stress for the risk stratification of bicuspid aortic valve aortopathy: A systematic review

JJ Qin, P Obeidy, M Gok, A Gholipour… - Frontiers in …, 2023 - frontiersin.org
Purpose Current intervention guidelines for bicuspid aortic valve (BAV) associated
ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome. There is …