A new liquid chromatography–electrospray ionization mass spectrometry (LC–ESI-MS)
method for the fast determination of phospholipase A2 (PLA2) activity has been developed …

Inflammation is a biological response of vascularized tissues to infections and damaged
tissues caused by injury, infection, malignancy, and cellular changes. The function of …

We have studied secretory phospholipase A2-IIA (sPLA2) activity toward different
phospholipid analogues by performing biophysical characterizations and molecular …

Isolated bovine neutrophils were used to study the relationship between the duration and
magnitude of the Mannheimia haemolytica leukotoxin-induced increase in intracellular …

Ceramide has been suggested to function as a mediator of exocytosis in response to the
addition of a calcium ionophore from PC12 cells. Here, we show that although cell …

Secretory class V phospholipase A2 (PLA2-V) has been shown to be involved in
inflammatory processes in cellular studies, but the biochemical and physical properties of …

The mechanisms of secretory phospholipase A2 (sPLA2) action are not understood clearly.
Previously, it was suggested that sPLA2s are internalized into cells for the targeting of …

We found that group IB secretory phospholipase A2 (sPLA2-IB) stimulates leukotriene B4
(LTB4) production in the absence of cytochalasin B in human neutrophils. Although LTB4 …

Abstract Changes in activity of phospholipase A 2 (PLA 2), a key enzyme in lipid metabolism
and signal network in defence mechanisms, were investigated in Solanum species and …

Secretory phospholipase A2 (sPLA2) represents a family of isoenzymes that participate in
lipoprotein and inflammatory pathways, mediate atherosclerosis and enhance myocardial …