Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Normal circulatory function is a key determinant of disease-free life expectancy (healthspan).
Indeed, pathologies affecting the cardiovascular system, which are growing in prevalence …

Scientists have been trying to identify every gene in the human genome since the initial draft
was published in 2001. In the years since, much progress has been made in identifying …

The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …

Cancer is the main cause of death worldwide and metastasis is a major cause of poor
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …

Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast
function play critical roles in bone formation, which is a highly regulated process. Long …

Abstract Ulcerative colitis (UC), Crohn's disease (CD), and celiac disease are prevalent
intestinal inflammatory disorders with nonsatisfactory therapeutic interventions. Analyzing …

More than 25 years after its discovery, the post-transcriptional gene regulation mechanism
termed RNAi is now transforming pharmaceutical development, proved by the recent FDA …

Gastric cancer (GC) represents~ 10% of the global cancer-related deaths, increasingly
affecting the younger population in active stages of life. The high mortality of GC is due to …