V Pannu, N Udongwo, S Imburgio… - Annals of …, 2024 - journals.sagepub.com
Background: Over the past 2 years of the several strategies recommended to help fight COVID-19, nirmatrelvir/ritonavir is a novel drug shown in the EPIC-HR phase 2 to 3 clinical …
Cold water benthic environments are a prolific source of structurally diverse molecules with a range of bioactivities against human disease. Specimens of a previously chemically …
N Rahimi-Levene, J Shapira, I Tzur, E Shiloah, V Peer… - Plos one, 2022 - journals.plos.org
Several options to treat hospitalized severe COVID-19 patients have been suggested. The study aimed to describe survival in patients treated with convalescent COVID plasma (CCP) …
A Favilli, M Mattei Gentili, F De Paola… - Journal of Personalized …, 2023 - mdpi.com
The COVID-19 pandemic posed a significant challenge for clinicians in managing pregnant women, who were at high risk of virus transmission and severe illness. While the WHO …
F Nappi, A Iervolino, SS Avtaar Singh - Biomedicines, 2022 - mdpi.com
The COVID-19 pandemic has resulted in a complex clinical challenge, caused by a novel coronavirus, partially similar to previously known coronaviruses but with a different pattern of …
Inflammatory cascades of the dysregulated inflammatory pathways in COVID-19 can cause excessive production of pro-inflammatory cytokines and chemokines leading to cytokine …
DS Mathew, T Pandya, H Pandya, Y Vaghela… - Biomolecules, 2023 - mdpi.com
The Coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has significantly impacted the health and …
LA St Clair, LLY Chan, A Boretsky, B Lin… - Journal of …, 2024 - Springer
The COVID-19 pandemic has created a worldwide public health crisis that has since resulted in 6.8 million reported deaths. The pandemic prompted the immediate response of …
W Obermann, A Friedrich, R Madhugiri, P Klemm… - Viruses, 2022 - mdpi.com
Rocaglates are potent broad-spectrum antiviral compounds with a promising safety profile. They inhibit viral protein synthesis for different RNA viruses by clamping the 5′-UTRs of …