Reversed chloroquine (RCQ) is a multiple ligand compound active against chloroquine-
sensitive and resistant falciparum malaria. It is composed by a 4-aminoquinoline moiety (like …

Malaria is one of the foremost public health problems in developing countries affecting
nearly 40% of the global population. Apart from this, the past two decade's emergence of …

Malaria is still considered the most threatening disease in Africa. Plasmodium; the malaria
parasite, forms during its intra-erythrocytic stage a pigment called hemozoin, which acts as a …

Aim: Garlic (Allium sativum L) aqueous extract was investigated to identify antimalarial
compounds inhibiting heme polymerization. Methods: Solvent fraction of aqueous garlic …

Blood‐stage malarial parasites are responsible for clinical manifestations of the disease.
During its proliferation, the parasite digests the host protein hemoglobin within the …

The aim of the study is to assess the effect of Palestinian flora Artemisia sieberi extract
against the formation of β-hematin in-vitro. β-hematin is a synthetic polymer made of …

Background and objectives: There are several methods to assess the in vitro capability of
heme inhibitory activity of antimalarial compounds; most of them require some specific …

Malaria remains a global threat with millions of deaths annually. Emergence of parasite
strains resistant to widely used antimalarials, including the artemisinin combination therapy …

In this study, metal oxide (MO) nanoparticles were synthesized using a microwave and
chemical methods and characterized using spectroscopic and microscopic techniques such …

A nitrogen-based ligand (pyridine-2-yl-undecyl-amine)(1) was synthesized and used for the
synthesis of a Zn (II) compound (dichloro-bis (pyridine-2-yl-undecyl-amine) zinc (II))(2) …