In vitro antiplasmodial activity and prophylactic potentials of extract and fractions of Trema orientalis (Linn.) stem bark

JO Olanlokun, OM David, AJ Afolayan - BMC complementary and …, 2017 - Springer
Background Trema orientalis (T. orientalis Linn) has been used in the management of
malaria in the western part of Nigeria and despite its application in ethnomedicine, there is …

Interpretation of the ultraviolet-visible spectra of malaria parasite Plasmodium falciparum

YM Serebrennikova, J Patel, LH Garcia-Rubio - Applied optics, 2010 - opg.optica.org
The absorption and scattering properties of three developmental stages of protozoan
parasite Plasmodium falciparum were studied both experimentally and theoretically …

Biological Evaluation and X‐ray Co‐crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of …

R De Gasparo, E Brodbeck‐Persch, S Bryson… - …, 2018 - Wiley Online Library
The tropical diseases human African trypanosomiasis, Chagas disease, and the various
forms of leishmaniasis are caused by parasites of the family of trypanosomatids. These …

Insights in chloroquine action: perspectives and implications in Malaria and COVID‐19

MM Pillat, A Krüger, LMF Guimarães, C Lameu… - Cytometry Part …, 2020 - Wiley Online Library
Malaria is a threat to human mankind and kills about half a million people every year. On the
other hand, COVID‐19 resulted in several hundred thousand deaths since December 2019 …

Drug resistance in malaria-in a nutshell

D Bhattacharjee, G Shivaprakash - Journal of Applied …, 2016 - japsonline.com
One peek into the history of malaria, shows us that despite many attempts by mankind to
counter the development and propagation of malaria, it has always risen back like a …

Antimalarial and antioxidant activities of novel artesunate-ellagic acid hybrid compound in vitro and in vivo

AA Ishola, JO Adebayo, IP Ceravolo, H Tijjani… - Frontiers in …, 2024 - frontiersin.org
Introduction: Emergence of drug resistant strains of Plasmodium species has necessitated
the search for novel antimalarials with unique mechanisms of action. Synthesis of hybrid …

Influence of N-protonation on electronic properties of acridine derivatives by quantum crystallography

S Pawlędzio, M Ziemniak, D Trzybiński… - RSC …, 2024 - pubs.rsc.org
Applications of 9-aminoacridine (9aa) and its derivatives span fields such as chemistry,
biology, and medicine, including anticancer and antimicrobial activities. Protonation of such …

Proteomic analysis of Plasmodium falciparum response to isocryptolepine derivative

K Rujimongkon, M Mungthin, J Tummatorn… - PLoS …, 2019 - journals.plos.org
Drug-resistant strains of malaria parasites have emerged for most of antimalarial
medications. A new chemotherapeutic compound is needed for malarial therapy …

Redox modulating small molecules having antimalarial efficacy

C Pal - Biochemical Pharmacology, 2023 - Elsevier
The search for effective antimalarial agents remains a critical priority because malaria is
widely spread and drug-resistant strains are becoming more prevalent. In this review, a …

[HTML][HTML] Effect of medium ph and light on quinidine production in Cinchona calisaya wedd. endophytic fungi

I Rahmawati, G Rahayu, D Ratnadewi… - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Objectives: Quinidine has pharmaceutical importance as an antimalarial, antiarrhythmia,
antimicrobial, anticancer, antioxidant, astringent, and bitter flavoring agent. Quinidine is in …