Quindolone derivatives, designed to target the malaria parasite digestive vacuole and heme
detoxification pathway, have been synthesized by reaction with 2-chloro-N, N …

Despite global efforts aimed at its elimination, malaria is still a significant health concern in
many countries across the world. The disease is caused by blood-borne parasites …

Hemozoin is a unique biomineral that results from the sequestration of toxic free heme
liberated as a consequence of hemoglobin degradation in the malaria parasite. Synthetic …

The rapid spread of strains of malaria parasites that are resistant to several drugs has
threatened global malaria control. Hence, the aim of this study was to predict the antimalarial …

Naphthoquine is a promising candidate for antimalarial combination therapy. Its combination
with artemisinin has demonstrated excellent efficacy in clinical trials conducted across …

Malaria remains one of the prominent public health problems that lead to severe morbidity
and mortality in many developing countries around the globe. New antimalarial drugs are …

Ethnopharmacological relevance Malaria eradication has been a major goal of the
Indonesian government since 2020. Medicinal plants, such as Strychnos lucida R. Br., are …

Plasmodium falciparum, the most deadly human malaria parasite, poses a major threat to
human health worldwide, with over 500 million clinical cases and between one and two …

New N-(7-chloroquinolinyl-4-aminoalkyl) arylsulfonamides were synthesized and tested in
vitro against P. falciparum 3D7 and K1 strains and hemozoin formation. Compounds 16 and …

An experimental in vitro study to evaluate the antimalarial activity of select homeopathy
preparations Page 1 International Journal of Medical and Health Research 65 International …