Microglia are the tissue-resident macrophage population of the brain, specialized in
supporting the CNS environment and protecting it from endogenous and exogenous insults …

Microglia are the resident immune cells of the central nervous system that guarantee
immune surveillance and exert also a modulating role on neuronal synaptic development …

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease now well-
documented as having arisen commonly from a viral infection, but also from other external …

The construction of the blood–brain barrier (BBB), which is a natural barrier for maintaining
brain homeostasis, is the result of a meticulous organisation in space and time of cell–cell …

Focused Ultrasound (FUS) paired with systemically-injected microbubbles (μB) is capable of
transiently opening the blood–brain barrier (BBBO) for noninvasive and targeted drug …

NADPH oxidases (Nox) are one of the main sources of reactive oxygen species (ROS) in the
central nervous system (CNS). While these enzymes have been shown to be involved in …

Neurodegenerative diseases (NDs) are a major cause of disability and are related to brain
development. The neurological signs of brain lesions can vary from mild clinical shortfalls to …

Increasing evidence has confirmed that the nervous system shows innate and adaptive
immunity, which also participates in nerve damage. This study aimed to explore the …

Aging can cause attenuation in the functioning of multiple organs, and blood-brain barrier
(BBB) breakdown could promote the occurrence of disorders of the central nervous system …

The relationship between inflammation and age-related neurocognitive changes is
significant, which may relate to the age-related immune dysfunctions characterized by the …