Relation Between Obesity and Type 2 Diabetes: Evolutionary Insights, Perspectives and Controversies

MK Gupta, G Gouda, R Vadde - Current Obesity Reports, 2024 - Springer
Abstract Purpose of Review Since the mid-twentieth century, obesity and its related
comorbidities, notably insulin resistance (IR) and type 2 diabetes (T2D), have surged …

[HTML][HTML] Novel inflammatory and insulin resistance indices provide a clue in cerebral amyloid angiopathy

H Zhu, Y Wang, L He, H Luo, C Zong, Y Yang… - Scientific Reports, 2024 - nature.com
This study investigated the correlation of newly identified inflammatory and insulin
resistance indices with cerebral amyloid angiopathy (CAA), and explored their potential to …

[HTML][HTML] Associations of Triglycerides and Atherogenic Index of Plasma with Brain Structure in the Middle-Aged and Elderly Adults

X Chen, Y Bao, J Zhao, Z Wang, Q Gao, M Ma, Z Xie… - Nutrients, 2024 - mdpi.com
Triglyceride (TG) and atherogenic index of plasma (AIP) have been acknowledged to be risk
factors for vascular insults, but their impacts on the brain system remain elusive. To fill in …

[HTML][HTML] Exploring blood lipids-immunity associations following HBV vaccination: evidence from a large cross-sectional study

Q Yang, B Li, T Luan, X Wang, B Duan… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Serological responses following hepatitis B vaccination are crucial for
preventing hepatitis B (HBV). However, the potential relationship between serum lipid levels …

Associations of glycosylated hemoglobin, pre-diabetes, and type 2 diabetes with incident lung cancer: A large prospective cohort study

J Hua, H Lin, X Wang, ZM Qian, MG Vaughn… - Diabetes & Metabolic …, 2024 - Elsevier
Background The association of pre-diabetes and type 2 diabetes (T2D) with incident lung
cancer is uncertain, and the incident risk across the glycemic spectrum is unclear. We aimed …

Relationship between indices of insulin resistance and incident type 2 diabetes mellitus in Chinese adults

Y Qin, Y Qiao, G Yan, D Wang, C Tang - Endocrine, 2024 - Springer
Background Insulin resistance (IR) is a pivotal pathogenesis characteristic of type 2 diabetes
mellitus (T2DM). The current study aimed to explore the association between …

[HTML][HTML] Functional interrogation of cellular Lp (a) uptake by genome-scale CRISPR screening

TG Khan, JB Cunha, C Raut, M Burroughs… - bioRxiv, 2024 - ncbi.nlm.nih.gov
An elevated level of lipoprotein (a), or Lp (a), in the bloodstream has been causally linked to
the development of atherosclerotic cardiovascular disease and calcific aortic valve stenosis …

Role of Blood Lipids in the Shared Genetic Etiology Between Major Depressive Disorder and Myocardial Infarction: A Large-scale Multi-trait Association Analysis

Y Zhu, Z Wu, Y Wang, Z Cui, F Liu, J Hu - medRxiv, 2024 - medrxiv.org
Background: The genetic role of blood lipids (BL) in the shared genetic etiology between
major depressive disorder (MDD) and myocardial infarction (MI) has not been fully …