The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …

Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is
etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke …

Experimental studies reported biochemical actions underpinning aging processes and
mortality, but the relevant metabolic alterations in humans are not well understood. Here we …

Ceramides, composed of a sphingosine and a fatty acid, are bioactive lipid molecules
involved in many key cellular pathways (eg, apoptosis, oxidative stress and inflammation) …

Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD) and
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …

Ceramides are a family of lipid molecules, composed of sphingosine and a fatty acid, and
transported by lipoproteins (primarily by low-density lipoproteins) in the bloodstream. They …

Cerebrovascular diseases and the subsequent brain hypoperfusion are at the basis of
vascular dementia. Dyslipidemia, marked by an increase in circulating levels of triglycerides …

Lipids are a complex group of molecules in the body, essential as structural, functional and
metabolic components. When disbalanced, they are regarded as a cardiovascular risk …

The spontaneous self-assembly of biomolecules around the surface of nanoparticles (NPs)
once exposed to plasma and other biofluids, has been termed the 'biomolecule corona' …

The medical community recognizes sex-related differences in pathophysiology and
cardiovascular disease outcomes (CVD), culminating with heart failure. In general, pre …