Drug repositioning based on tripartite cross-network embedding and graph convolutional network

P Zeng, B Zhang, A Liu, Y Meng, X Tang, J Yang… - Expert Systems with …, 2024 - Elsevier
Drug-disease association prediction is an important part of drug discovery, which can help
researchers uncover potential drug candidates and disease targets more accurately to deal …

SGCLDGA: unveiling drug–gene associations through simple graph contrastive learning

Y Fan, C Zhang, X Hu, Z Huang, J Xue… - Briefings in …, 2024 - academic.oup.com
Drug repurposing offers a viable strategy for discovering new drugs and therapeutic targets
through the analysis of drug–gene interactions. However, traditional experimental methods …

SDDSynergy: Learning Important Molecular Substructures for Explainable Anticancer Drug Synergy Prediction

Y Liu, P Zhang, C Che, Z Wei - Journal of Chemical Information …, 2024 - ACS Publications
Drug combination therapies are well-established strategies for the treatment of cancer with
low toxicity and fewer adverse effects. Computational drug synergy prediction approaches …

Antibiotic Bacteria Interaction: Dataset and Benchmarking.

S Chatterjee, A Majumdar, E Chouzenoux - bioRxiv, 2024 - biorxiv.org
This study introduces a dataset for drug-bacteria associations (DBA) that affects humans.
Our contribution extends beyond merely curating the association matrix; we also conduct …

KSGTN-DDI: Key Substructure-aware Graph Transformer Network for Drug-drug Interaction Prediction

P Zhang, Y Liu, Z Shen - 2023 IEEE International Conference …, 2023 - ieeexplore.ieee.org
Drug substructure plays a crucial role in predicting drug-drug interaction (DDI) with
combination drugs for disease therapies. In order to exploit the effect of drug substructure on …