Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide.
Tyrosine kinase inhibitors (TKIs) remain the backbone of systematic therapy for advanced …

Hepatocellular carcinoma (HCC) represents the third cause of cancer death in men
worldwide, and its increasing incidence can be explained by the increasing occurrence of …

N-glycosylation is one of the most common types of protein modifications and it plays a vital
role in normal physiological processes. However, aberrant N-glycan modifications are …

Background The mechanism of cuproptosis has recently been reported in lipoylated proteins
of the tricarboxylic acid (TCA) cycle. Besides, the role of copper was previously recognized …

Hepatocellular carcinoma (HCC) was the third most common cause of cancer death. But it
has only limited therapeutic options, aggressive nature, and very low overall survival …

Background Accumulating studies have demonstrated that the Warburg effect plays a central
role in the occurrence and development of hepatocellular carcinoma (HCC), albeit the role …

Hepatocellular carcinoma (HCC) is commonly associated with disturbances in glucose
metabolism and enhanced glycolysis. However, a controversial role for gluconeogenesis …

Background This study aimed to examine glycolysis/gluconeogenesis-related genes in
hepatocellular carcinoma (HCC) and evaluate their potential roles in HCC progression and …

miR-22 is one of the most abundant miRNAs in the liver and alterations of its hepatic
expression have been associated with the development of hepatic steatosis and insulin …

Mitochondria are double-membrane organelles that are involved in energy production,
apoptosis, and signaling in eukaryotic cells. Several studies conducted over the past …