Intranasal vaccines for SARS-CoV-2: From challenges to potential in COVID-19 management

VP Chavda, LK Vora, AK Pandya, VB Patravale - Drug discovery today, 2021 - Elsevier
Abstract Unlike conventional Coronavirus 2019 (COVID-19) vaccines, intranasal vaccines
display a superior advantage because the nasal mucosa is often the initial site of infection …

COVID-19 and corticosteroids: a narrative review

G El-Saber Batiha, AI Al-Gareeb, HM Saad… - …, 2022 - Springer
It has been reported that corticosteroid therapy was effective in the management of severe
acute respiratory syndrome (SARS) and the Middle East Respiratory Syndrome (MERS) …

Inhaled corticosteroids for the treatment of COVID-19

M Bafadhel, R Faner, C Taillé… - European …, 2022 - Eur Respiratory Soc
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused
severe illness and mortality for millions worldwide. Despite the development, approval and …

Ciclesonide inhaler treatment for mild-to-moderate COVID-19: a randomized, open-label, phase 2 trial

JY Song, JG Yoon, YB Seo, J Lee, JS Eom… - Journal of Clinical …, 2021 - mdpi.com
Although some intravenous drugs have been used to treat coronavirus disease 2019
(COVID-19), no effective antiviral agents are currently available in the outpatient setting. We …

Inhaled corticosteroids for the treatment of COVID‐19

Cochrane Airways Group, M Griesel… - Cochrane Database …, 1996 - cochranelibrary.com
Background Inhaled corticosteroids are well established for the long‐term treatment of
inflammatory respiratory diseases such as asthma or chronic obstructive pulmonary disease …

Impact of inhaled ciclesonide on asymptomatic or mild COVID-19: a randomized trial

J Terada-Hirashima, M Suzuki, Y Tsujimoto… - Drug Discoveries & …, 2022 - jstage.jst.go.jp
The aim of this study was to determine the efficacy and safety of ciclesonide in the treatment
of novel coronavirus disease 2019 (COVID-19) as gauged by pneumonia progression. This …

COVID-19 and bronchial asthma: current perspectives

M Hojo, J Terada-Hirashima… - Global Health & Medicine, 2021 - jstage.jst.go.jp
Angiotensin converting enzyme 2 (ACE2) and transmembrane protease serine 2
(TMPRSS2), two receptors on the cell membrane of bronchial epithelial cells, are …

[HTML][HTML] Variations of SARS-CoV-2 in the Iranian population and candidate putative drug-like compounds to inhibit the mutated proteins

Z Mortezaei, A Mohammadian, M Tavallaei - Heliyon, 2022 - cell.com
The first cases of the novel coronavirus, SARS-CoV-2, were detected in December 2019 in
Wuhan, China. Nucleotide substitutions and mutations in the SARS-CoV-2 sequence can …

Favipiravir, camostat, and ciclesonide combination therapy in patients with moderate COVID-19 pneumonia with/without oxygen therapy: An open-label, single-center …

J Terada, R Fujita, T Kawahara, Y Hirasawa… - …, 2022 - thelancet.com
Background The effectiveness of combination therapy for COVID-19 pneumonia remains
unclear. We evaluated favipiravir, camostat, and ciclesonide combination therapy in patients …

[PDF][PDF] Could inhaled corticosteroids be the game changers in the prevention of severe COVID-19? A review of current evidence

P Medica - Panminerva medica, 2021 - academia.edu
More than a year after the first outbreak in Wuhan, China the pandemic caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), named coronavirus …