[HTML][HTML] GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives

R Nevola, R Epifani, S Imbriani, G Tortorella… - International Journal of …, 2023 - mdpi.com
To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease,
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …

[HTML][HTML] Peripheral neuropathy in diabetes mellitus: pathogenetic mechanisms and diagnostic options

R Galiero, A Caturano, E Vetrano, D Beccia… - International Journal of …, 2023 - mdpi.com
Diabetic neuropathy (DN) is one of the main microvascular complications of both type 1 and
type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis …

[HTML][HTML] Metabolic-associated fatty liver disease (MAFLD), diabetes, and cardiovascular disease: Associations with fructose metabolism and gut microbiota

K Drożdż, K Nabrdalik, W Hajzler, H Kwiendacz… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition associated
with type 2 diabetes (T2DM) and cardiovascular disease (CVD). Since systemic metabolic …

[HTML][HTML] Effects of metformin in heart failure: From pathophysiological rationale to clinical evidence

T Salvatore, R Galiero, A Caturano, E Vetrano… - Biomolecules, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a worldwide major health burden and heart failure (HF)
is the most common cardiovascular (CV) complication in affected patients. Therefore …

[HTML][HTML] Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies

E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …

[HTML][HTML] Cardiovascular benefits from gliflozins: effects on endothelial function

T Salvatore, A Caturano, R Galiero, A Di Martino… - Biomedicines, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a known independent risk factor for atherosclerotic
cardiovascular disease (CVD) and solid epidemiological evidence points to heart failure …

Protective effects of metformin in various cardiovascular diseases: clinical evidence and AMPK‐dependent mechanisms

Y Bu, M Peng, X Tang, X Xu, Y Wu… - Journal of Cellular …, 2022 - Wiley Online Library
Metformin, a well‐known AMPK agonist, has been widely used as the first‐line drug for
treating type 2 diabetes. There had been a significant concern regarding the use of …

Role of inflammation in diabetic cardiomyopathy

P Ramesh, JL Yeo, EM Brady… - … in Endocrinology and …, 2022 - journals.sagepub.com
The prevalence of type 2 diabetes (T2D) has reached a pandemic scale. Systemic chronic
inflammation dominates the diabetes pathophysiology and has been implicated as a causal …

[HTML][HTML] Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes

T Salvatore, R Galiero, A Caturano, E Vetrano… - Biomolecules, 2022 - mdpi.com
Cardiovascular (CV) disease and heart failure (HF) are the leading cause of mortality in type
2 diabetes (T2DM), a metabolic disease which represents a fast-growing health challenge …

[PDF][PDF] Bocs, an

PM Boarescu, I Boarescu, RM Pop, SH Rosian - Int. J. Mol. Sci, 2022 - academia.edu
The present study aims to compare the oxidative stress biomarkers, pro-inflammatory
cytokines, and histological changes induced by three cardiovascular risk factors, namely …