[HTML][HTML] Associations of combined phenotypic aging and genetic risk with incident cancer: A prospective cohort study
L Bian, Z Ma, X Fu, C Ji, T Wang, C Yan, J Dai, H Ma… - Elife, 2024 - elifesciences.org
Background: Age is the most important risk factor for cancer, but aging rates are
heterogeneous across individuals. We explored a new measure of aging-Phenotypic Age …
heterogeneous across individuals. We explored a new measure of aging-Phenotypic Age …
Lifestyle Factors and Metabolomic Aging Biomarkers: Meta-analysis of Cross-sectional and Longitudinal Associations in Three Prospective Cohorts
LM Kuiper, AP Smit, D Bizzarri… - Mechanisms of Ageing …, 2024 - Elsevier
Biological age uses biophysiological information to capture a person's age-related risk of
adverse outcomes. MetaboAge and MetaboHealth are metabolomics-based biomarkers of …
adverse outcomes. MetaboAge and MetaboHealth are metabolomics-based biomarkers of …
Decoding Human Biology and Disease Using Single-cell Omics Technologies
Q Shi, X Chen, Z Zhang - Genomics, Proteomics & …, 2023 - academic.oup.com
Over the past decade, advances in single-cell omics (SCO) technologies have enabled the
investigation of cellular heterogeneity at an unprecedented resolution and scale, opening a …
investigation of cellular heterogeneity at an unprecedented resolution and scale, opening a …
[HTML][HTML] Development of a model for the prediction of biological age
X Ni, H Zhao, R Li, H Su, J Jiao, Z Yang, Y Lv… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective Rates of aging vary markedly among individuals, and
biological age serves as a more reliable predictor of current health status than does …
biological age serves as a more reliable predictor of current health status than does …
Inhibiting arachidonic acid generation mitigates aging-induced hyperinsulinemia and insulin resistance in mice
X Xiao, L Yang, L Xiao, Y Li, X Chang, X Han, W Tang… - Clinical Nutrition, 2024 - Elsevier
Background Aging-related type 2 diabetes (T2DM) is characterized by hyperinsulinemia,
insulin resistance, and β-cell dysfunction. However, the underlying molecular mechanisms …
insulin resistance, and β-cell dysfunction. However, the underlying molecular mechanisms …
[HTML][HTML] Progress in the study of aging marker criteria in human populations
Y He, Z Li, Y Niu, Y Duan, Q Wang, X Liu… - Frontiers in Public …, 2024 - frontiersin.org
The use of human aging markers, which are physiological, biochemical and molecular
indicators of structural or functional degeneration associated with aging, is the fundamental …
indicators of structural or functional degeneration associated with aging, is the fundamental …
[HTML][HTML] Unraveling the Potential of Attentive Bi-LSTM for Accurate Obesity Prognosis: Advancing Public Health towards Sustainable Cities
H Ayub, MA Khan, S Shehryar Ali Naqvi, M Faseeh… - Bioengineering, 2024 - mdpi.com
The global prevalence of obesity presents a pressing challenge to public health and
healthcare systems, necessitating accurate prediction and understanding for effective …
healthcare systems, necessitating accurate prediction and understanding for effective …
[HTML][HTML] Partnership status and positive DNA methylation age acceleration across the adult lifespan in the UK
Although a significant body of research has shown that married people are healthier and live
longer, empirical research on sex differences in the link between marital status and health …
longer, empirical research on sex differences in the link between marital status and health …
Epigenetic clock: future of hypertension prediction?
XM Wang, HP Wang, HZ Chen, DP Liu - Hypertension, 2023 - Am Heart Assoc
In the current issue of Hypertension, Jacob et al1 revealed the intriguing associations
between hypertension and blood DNA methylation, advancing our understanding of the …
between hypertension and blood DNA methylation, advancing our understanding of the …
[HTML][HTML] Evolutionary screening of precision oncology biomarkers and its applications in prognostic model construction
ZW Zhang, KX Zhang, X Liao, Y Quan, HY Zhang - Iscience, 2024 - cell.com
Biomarker screening is critical for precision oncology. However, one of the main challenges
in precision oncology is that the screened biomarkers often fail to achieve the expected …
in precision oncology is that the screened biomarkers often fail to achieve the expected …