[HTML][HTML] Targeting Inflammasome activation in viral infection: a therapeutic solution?
Inflammasome activation is exclusively involved in sensing activation of innate immunity and
inflammatory response during viral infection. Accumulating evidence suggests that the …
inflammatory response during viral infection. Accumulating evidence suggests that the …
Gestational diabetes mellitus in the era of COVID-19: Challenges and opportunities
Y Xing, H Wang, C Chao, X Ding, G Li - Diabetes & Metabolic Syndrome …, 2024 - Elsevier
Background and aims The impact of the coronavirus disease 2019 (COVID-19) pandemic on
pregnant women, especially those with gestational diabetes mellitus (GDM), has yet to be …
pregnant women, especially those with gestational diabetes mellitus (GDM), has yet to be …
[HTML][HTML] On fine particulate matter and COVID-19 spread and severity: An in vitro toxicological plausible mechanism
COVID-19 pandemic had a significant impact on global public health. The spread of the
disease was related to the high transmissibility of SARS-CoV-2 virus but incidence and …
disease was related to the high transmissibility of SARS-CoV-2 virus but incidence and …
[HTML][HTML] SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naive mice
JDS Willett, A Gravel, I Dubuc, L Gudimard… - Communications …, 2024 - nature.com
The persistence of SARS-CoV-2 despite the development of vaccines and a degree of herd
immunity is partly due to viral evolution reducing vaccine and treatment efficacy. Serial …
immunity is partly due to viral evolution reducing vaccine and treatment efficacy. Serial …
COVID-19 Vaccine in Immunosuppressed Adults with Autoimmune rheumatic Diseases (COVIAAD): safety, immunogenicity and antibody persistence at 12 months …
I Colmegna, V Valerio, N Amiable, M Useche… - RMD open, 2023 - rmdopen.bmj.com
Objective To assess the safety, immunogenicity and cellular responses following the
Moderna Spikevax primary series in rheumatic disease. Methods We conducted a 12-month …
Moderna Spikevax primary series in rheumatic disease. Methods We conducted a 12-month …
[HTML][HTML] Aesculus hippocastanum extract and the main bioactive constituent β-escin as antivirals agents against coronaviruses, including SARS-CoV-2
FA Peñaranda Figueredo, J Vicente, AA Barquero… - Scientific Reports, 2024 - nature.com
Respiratory viruses can cause life-threatening illnesses. The focus of treatment is on
supportive therapies and direct antivirals. However, antivirals may cause resistance by …
supportive therapies and direct antivirals. However, antivirals may cause resistance by …
[HTML][HTML] Novel mutations in the non-structure protein 2 of SARS-CoV-2
M Nakhaie, MRZ Rukerd, H Askarpour… - … Journal of Hematology …, 2023 - ncbi.nlm.nih.gov
Results The patients' mean age was 51.08. The results revealed that 8 of the 17 NSP2
mutations (R207C, T224I, G262V, T265I, K337D, N348S, G392D, and I431M) were …
mutations (R207C, T224I, G262V, T265I, K337D, N348S, G392D, and I431M) were …
[HTML][HTML] Comparative transcriptome analysis of SARS-CoV-2, SARS-CoV, MERS-CoV, and HCoV-229E identifying potential IFN/ISGs targets for inhibiting virus …
Y Liu, T Lu, C Li, X Wang, F Chen, L Yue… - Frontiers in …, 2023 - frontiersin.org
Introduction Since its outbreak in December 2019, SARS-CoV-2 has spread rapidly across
the world, posing significant threats and challenges to global public health. SARS-CoV-2 …
the world, posing significant threats and challenges to global public health. SARS-CoV-2 …
[HTML][HTML] Association between dietary inflammatory index and chronic kidney disease in middle-aged and elderly populations
M Guo, Y Lei, X Liu, X Li, Y Xu, D Zheng - Frontiers in Nutrition, 2024 - frontiersin.org
Background A link between food-induced inflammation and common chronic diseases has
been identified in studies. However, there was uncertainty about the influence of dietary …
been identified in studies. However, there was uncertainty about the influence of dietary …
Natural evolution of SARS-CoV-2 variants in K18-ACE2 mice gives rise to more virulent virus and variant alleles associated with treatment resistance
JD Sunday Willett, A Gravel, I Dubuc, L Gudimard… - bioRxiv, 2023 - biorxiv.org
Background The continuing COVID-19 pandemic is partially due to viral evolution
decreasing vaccine and treatment efficacies. Predicting viral evolution is difficult. Others …
decreasing vaccine and treatment efficacies. Predicting viral evolution is difficult. Others …