[HTML][HTML] Friend or foe? Defining the role of glutamate in aging and Alzheimer's disease

MKF Cox, ER Hascup, A Bartke, KN Hascup - Frontiers in Aging, 2022 - frontiersin.org
Aging is a naturally occurring decline of physiological processes and biological pathways
that affects both the structural and functional integrity of the body and brain. These …

[HTML][HTML] The role of cannabidiol in aging

B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …

[HTML][HTML] mTOR and SGLT-2 Inhibitors: Their Synergistic Effect on Age-Related Processes

D Troise, S Mercuri, B Infante, V Losappio… - International journal of …, 2024 - mdpi.com
The aging process contributes significantly to the onset of chronic diseases, which are the
primary causes of global mortality, morbidity, and healthcare costs. Numerous studies have …

[HTML][HTML] Geroprotective activity of trans-cinnamic acid isolated from the Baikal skullcap (Scutellaria baicalensis)

KM El Amine - Техника и технология пищевых производств, 2022 - cyberleninka.ru
Trans-cinnamic acid is a phenolic compound with a wide range of bioactive properties,
including antioxidant and antibacterial effects. It also has high potential in the food and …

Drugs and endogenous factors as protagonists in neurogenic stimulation

RA Chiareli, BL Marques, GA de Carvalho… - Stem Cell Reviews and …, 2022 - Springer
Neurogenesis is a biological process characterized by new neurons formation from stem
cells. For decades, it was believed that neurons only multiplied during development and in …

[HTML][HTML] Aging is a Side Effect of the Ontogenesis Program of Multicellular Organisms

L Salnikov - Biochemistry (Moscow), 2022 - Springer
The review presents a brief outline of the current state of the main theoretical approaches to
the aging problem. The works of authors, supporting the theory of “accumulation of errors” …

[HTML][HTML] Pro-Aging Metabolic Reprogramming: A Unified Theory of Aging

Z Wang, B Yang - Engineering, 2024 - Elsevier
Despite recent advances in understanding the biology of aging, the field remains
fragmented due to the lack of a central organizing hypothesis. Although there are ongoing …

Urolithin A induces cardioprotection and enhanced mitochondrial quality during natural aging and heart failure

S Liu, J Faitg, C Tissot, D Konstantopoulos, R Laws… - bioRxiv, 2023 - biorxiv.org
Cardiovascular diseases remain the primary cause of global mortality, necessitating
effective strategies to alleviate their burden. Mitochondrial dysfunction is a driving force …

DNA methylation meta-analysis confirms the division of the genome into two functional groups

L Salnikov, S Goldberg, P Sukumaran, E Pinsky - bioRxiv, 2022 - biorxiv.org
Based on a meta-analysis of human genome methylation data, we tested a theoretical
model in which aging is explained by the redistribution of limited resources in cells between …

In vitro and In vivo Studies on Nutraceutical Treatment Strategies to Promote Healthy Ageing in Some of the Major Age-related Diseases

S Ruga - 2023 - tesidottorato.depositolegale.it
One of the global problems of humanity is preserving the quality of life as the average age of
the populationrises. At the same time, a significant increase in the proportion of the elderly in …