Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals

K Sugden, TE Moffitt, TE Arpawong… - The Journals of …, 2023 - academic.oup.com
Objectives Individuals with more education are at lower risk of developing multiple, different
age-related diseases than their less-educated peers. A reason for this might be that …

LensAge index as a deep learning-based biological age for self-monitoring the risks of age-related diseases and mortality

R Li, W Chen, M Li, R Wang, L Zhao, Y Lin… - Nature …, 2023 - nature.com
Age is closely related to human health and disease risks. However, chronologically defined
age often disagrees with biological age, primarily due to genetic and environmental …

Associations of socioeconomic disparities with buccal DNA-methylation measures of biological aging

L Raffington, T Schwaba, M Aikins, D Richter… - Clinical …, 2023 - Springer
Background Individuals who are socioeconomically disadvantaged are at increased risk for
aging-related diseases and perform less well on tests of cognitive function. The weathering …

Cognitive aging and the life course: A new look at the scaffolding theory

PA Reuter-Lorenz, DC Park - Current Opinion in Psychology, 2023 - Elsevier
Our understanding of human neurocognitive aging, its developmental roots, and life course
influences has been transformed by brain imaging technologies, increasing availability of …

Human oligodendrocyte myelination potential; relation to age and differentiation

JXX Luo, QL Cui, M Yaqubi, JA Hall… - Annals of …, 2022 - Wiley Online Library
Objective Myelin regeneration in the human central nervous system relies on progenitor
cells within the tissue parenchyma, with possible contribution from previously myelinating …

Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop

TE Brinkley, JN Justice, S Basu, SR Bauer, KP Loh… - Geroscience, 2022 - Springer
Biologic aging reflects the genetic, molecular, and cellular changes underlying the
development of morbidity and mortality with advancing chronological age. As several …

Immunomodulation in age‐related disorders and nanotechnology interventions

U Chintapula, T Chikate, D Sahoo… - Wiley …, 2023 - Wiley Online Library
Recently, the aging population has increased exponentially around the globe bringing more
challenges to improve quality of life in those populations while reducing the economic …

Frailty and depression in late life: a high-risk comorbidity with distinctive clinical presentation and poor antidepressant response

PJ Brown, A Ciarleglio, SP Roose… - The Journals of …, 2022 - academic.oup.com
Background To investigate the longitudinal relationship between physical frailty, the clinical
representation of accelerated biological aging, and antidepressant medication response in …

Participant diversity is necessary to advance brain aging research

GS Wig, S Klausner, MY Chan, C Sullins… - Trends in cognitive …, 2024 - cell.com
An absence of population-representative participant samples has limited research in healthy
brain aging. We highlight examples of what can be gained by enrolling more diverse …

Socioeconomic status, biological aging, and memory in a diverse national sample of older US men and women

J Avila-Rieger, IC Turney, JMJ Vonk, P Esie… - Neurology, 2022 - AAN Enterprises
Background and Objectives Exposure to socioeconomic disadvantage is associated with
early-onset cognitive aging. Biological aging, the progressive loss of system integrity that …