Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance

LY Hung, KG Margolis - Nature Reviews Gastroenterology & …, 2024 - nature.com
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

Microbiota-Brain Axis: Exploring the Role of Gut Microbiota in Psychiatric Disorders-A Comprehensive Review

J Singh, A Singh, S Biswal, R Zomuansangi… - Asian Journal of …, 2024 - Elsevier
Mental illness is a hidden epidemic in modern science that has gradually spread worldwide.
According to estimates from the World Health Organization (WHO), approximately 10% of …

[HTML][HTML] A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis

JS Boles, ME Krueger, JE Jernigan, CL Cole… - Brain, Behavior, and …, 2024 - Elsevier
The gut and brain are increasingly linked in human disease, with neuropsychiatric
conditions classically attributed to the brain showing an involvement of the intestine and …

[HTML][HTML] Preliminary findings of elevated inflammatory plasma cytokines in children with autism who have co-morbid gastrointestinal symptoms

P Ashwood - Biomedicines, 2023 - mdpi.com
Autism spectrum disorder (AU) is present in approximately 2% of the population and is often
associated with co-morbidities that can impact quality of life. One of the most common co …

[HTML][HTML] Two-sample Mendelian randomization analysis investigates causal associations between gut microbiota and attention deficit hyperactivity disorder

L Wang, Z Xie, G Li, G Li, J Liang - Frontiers in Microbiology, 2023 - frontiersin.org
Previous research has suggested a link between gut microbiota and attention deficit
hyperactivity disorder (ADHD), but their causal relationship has not been elucidated. Aiming …

[HTML][HTML] The modulatory effects of gut microbes and metabolites on blood–brain barrier integrity and brain function in sepsis-associated encephalopathy

Z Li, F Zhang, M Sun, J Liu, L Zhao, S Liu, S Li, B Wang - PeerJ, 2023 - peerj.com
Background Intestinal microbiota homeostasis and the gut-brain axis are key players
associated with host health and alterations in metabolic, inflammatory, and …

[HTML][HTML] Altered gut microbiota in Taiwanese A97S predominant transthyretin amyloidosis with polyneuropathy

CC Chen, PH Tseng, HW Hsueh, MC Chiang… - Scientific Reports, 2024 - nature.com
Increasing evidence suggests that gut microbiota alterations are related to development and
phenotypes of many neuropsychiatric diseases. Here, we evaluated the fecal microbiota and …

[HTML][HTML] The alterations of gut microbiome and lipid metabolism in patients with spinal muscular atrophy

Y Feng, Y Cui, J Jin, S Huang, J Wei, M Yao… - Neurology and …, 2023 - Springer
Introduction Spinal muscular atrophy (SMA) can cause multiple system dysfunction,
especially lipid metabolic disorders, for which management strategies are currently lacking …

Precision synbiotics increase gut microbiome diversity and improve gastrointestinal symptoms in a pilot open-label study for autism spectrum disorder

J Phan, DC Calvo, D Nair, S Jain, T Montagne… - Msystems, 2024 - Am Soc Microbiol
The efficacy of prebiotics and probiotics (synbiotics when combined) to improve symptoms
associated with autism spectrum disorder (ASD) has shown considerable inter-study …

Gut microbiota composition links to variation in functional domains across psychiatric disorders

D Mulder, B Jakobi, Y Shi, P Mulders, JD Kist… - Brain, Behavior, and …, 2024 - Elsevier
Objective Changes in microbial composition are observed in various psychiatric disorders,
but their specificity to certain symptoms or processes remains unclear. This study explores …