Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

Background No study has gathered evidence from all randomized clinical trials (RCT s) with
anti‐inflammatory drugs measuring antidepressant effects including a detailed assessment …

Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …

Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

Many patients with major depressive disorder (MDD) are reported to have higher levels of
multiple inflammatory cytokines including interleukin 6 (IL-6). Recent studies both pre …

Mounting evidence suggests that aberrations in immune-inflammatory pathways contribute
to the pathophysiology of major depressive disorder (MDD), and individuals with MDD may …

BackgroundC-reactive protein (CRP) is a candidate biomarker for major depressive disorder
(MDD), but it is unclear how peripheral CRP levels relate to the heterogeneous clinical …

Objective Increased inflammation and oxidative stress have been shown in Major
Depressive Disorder (MDD), although there is significant heterogeneity across studies …

Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …

Depression is the most prevalent and among the most debilitating of psychiatric disorders.
The precise neurobiology of this illness is unknown. Several lines of evidence suggest that …