Xenotransplantation has the potential to address shortages of organs available for clinical
transplantation, but concerns exist regarding potential risks posed by porcine …

This review highlights the current progress in nonhuman primate models and recent reports
of human xenotransplantation. It also describes the remaining hurdles and currently …

There have been high expectations in recent years of using xenotransplantation and
regenerative medicine to treat humans, and pigs have been utilized as the donor model …

With decades of pre‐clinical studies culminating in the recent clinical application of
xenotransplantation, it would appear timely to provide recommendations for operationalizing …

The 2-month-survival of a terminally ill patient who received a genetically modified pig heart
has demonstrated that cardiac xenotransplantation could provide a therapeutic option for …

In this clinicopathological conference, invited experts discussed a previously published case
of a patient with nonischemic cardiomyopathy who underwent heart transplantation from a …

Abstract Background The German Xenotransplantation Consortium is in the process to
prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig …

Chronic kidney disease affects an estimated 37 million people in the United States; of
these,> 800,000 have end-stage renal disease requiring chronic dialysis or a kidney …

Abstract In June 2022, the US Food and Drug Administration Center for Biologics Evaluation
and Research held the 73rd meeting of the Cellular, Tissue, and Gene Therapies Advisory …

Background. Xenotransplantation clinical trials may begin soon. A persistent risk of
xenotransplantation, known for decades, is the possibility that a xenozoonotic infection could …