[HTML][HTML] Implications of NKG2A in immunity and immune-mediated diseases

X Wang, H Xiong, Z Ning - Frontiers in immunology, 2022 - frontiersin.org
In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer
(NK) cells and CD8+ T cells. It form heterodimer receptors with CD94, and targets the …

[HTML][HTML] Systemic inflammation index, disease severity, and mortality in patients with COVID-19: a systematic review and meta-analysis

AA Mangoni, A Zinellu - Frontiers in Immunology, 2023 - frontiersin.org
Introduction An excessive systemic pro-inflammatory state increases the risk of severe
disease and mortality in patients with coronavirus disease 2019 (COVID-19). However, there …

[HTML][HTML] Comparison of C-reactive protein with distinct hyperinflammatory biomarkers in association with COVID-19 severity, mortality and SARS-CoV-2 variants

TG Paranga, M Pavel-Tanasa… - Frontiers in …, 2023 - frontiersin.org
C-reactive protein (CRP) has been one of the most investigated inflammatory-biomarkers
during the ongoing COVID-19 pandemics caused by severe acute respiratory syndrome …

Dysregulation of glutamine/glutamate metabolism in COVID‐19 patients: A metabolism study in African population and mini meta‐analysis

X Li, B Tu, XA Zhang, W Xu, J Chen… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) remains a serious global threat. The
metabolic analysis had been successfully applied in the efforts to uncover the pathological …

[HTML][HTML] C-reactive protein and clinical outcome in COVID-19 patients: the importance of harmonized measurements

E Aloisio, G Colombo, A Dolci… - Clinical Chemistry and …, 2023 - degruyter.com
C-reactive protein (CRP) is a cytokine-mediated acute phase reactant with a recognized role
in inflammatory conditions and infectious disease. In coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Potential marker subset of blood-circulating cytokines on hematopoietic progenitor-to-Th1 pathway in COVID-19

Y Takashima, T Inaba, T Matsuyama, K Yoshii… - Frontiers in …, 2024 - frontiersin.org
In this study, we analyzed a relatively large subset of proteins, including 109 kinds of blood-
circulating cytokines, and precisely described a cytokine storm in the expression level and …

[HTML][HTML] Aggregate Index of Systemic Inflammation (AISI), Disease Severity, and Mortality in COVID-19: A Systematic Review and Meta-Analysis

A Zinellu, P Paliogiannis, AA Mangoni - Journal of Clinical Medicine, 2023 - mdpi.com
Combined indices of different haematological cell types appear to be particularly promising
for investigating the link between systemic inflammation and coronavirus disease 2019 …

[HTML][HTML] The GNB3 c.825C>T (rs5443) polymorphism and protection against fatal outcome of corona virus disease 2019 (COVID-19)

B Möhlendick, K Schönfelder, C Zacher, C Elsner… - Frontiers in …, 2022 - frontiersin.org
Background and aims: Albeit several factors which influence the outcome of corona virus
disease (COVID-19) are already known, genetic markers which may predict the outcome of …

[HTML][HTML] T-Cell subsets and interleukin-10 levels are predictors of severity and mortality in COVID-19: A systematic review and meta-analysis

AF Alshammary, JM Alsughayyir, KK Alharbi… - Frontiers in …, 2022 - frontiersin.org
Background: A large number of COVID-19 patients reveal a marked decrease in their
lymphocyte counts—a condition that translates clinically into the state of immunodepression …

[HTML][HTML] Predictive values of immune indicators on respiratory failure in the early phase of COVID-19 due to Delta and precedent variants

K Nagaoka, H Kawasuji, Y Takegoshi, Y Murai… - Frontiers in …, 2023 - frontiersin.org
Background Immune response indicators in the early phase of COVID-19, including
interferon and neutralizing responses against SARS-CoV-2, which predict hypoxemia …