Local and regional therapies for hepatocellular carcinoma

R Kloeckner, PR Galle, J Bruix - Hepatology, 2021 - Wiley Online Library
Local and regional therapies are recommended for patients with hepatocellular carcinoma
(HCC) in very early (Barcelona Clinic Liver Cancer [BCLC] 0), early (BCLC A), and …

New therapies for hepatocellular carcinoma

MA Avila, C Berasain, B Sangro, J Prieto - Oncogene, 2006 - nature.com
Hepatocellular carcinoma (HCC), one of the most common cancers worldwide, is often
diagnosed at an advanced stage when most potentially curative therapies such as resection …

Clinical trials with oncolytic adenovirus in China

W Yu, H Fang - Current cancer drug targets, 2007 - ingentaconnect.com
Since the 1990s, oncolytic viruses were utilized to treat cancer patients from phase I to
phase III. Oncolytic virus development in China has been keeping in step with that in other …

[HTML][HTML] Hepatocellular carcinoma: therapy and prevention

HE Blum - World journal of gastroenterology, 2005 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide.
The major etiologies and risk factors for the development of HCC are well defined and some …

Targeting apoptosis pathways in cancer therapy

S Fulda, KM Debatin - Current cancer drug targets, 2004 - ingentaconnect.com
Killing of tumor cells by anticancer therapies commonly used in the treatment of cancer, eg
chemotherapy, γ-irradiation, immunotherapy or suicide gene therapy, is predominantly …

[HTML][HTML] Mouse models of liver cancer: Progress and recommendations

L He, DA Tian, PY Li, XX He - Oncotarget, 2015 - ncbi.nlm.nih.gov
To clarify the pathogenesis of hepatocellular carcinoma (HCC) and investigate the effects of
potential therapies, a number of mouse models have been developed. Subcutaneous …

Silibinin efficacy against human hepatocellular carcinoma

L Varghese, C Agarwal, A Tyagi, RP Singh… - Clinical cancer …, 2005 - AACR
Purpose: Hepatocellular carcinoma (HCC) is one of the most common recurrent
malignancies, for which, currently, there is no effective therapy. Considering the …

Sulforaphane sensitizes tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)–resistant hepatoma cells to TRAIL-induced apoptosis through reactive …

H Kim, EH Kim, YW Eom, WH Kim, TK Kwon, SJ Lee… - Cancer research, 2006 - AACR
Sulforaphane is a chemopreventive agent present in various cruciferous vegetables,
including broccoli. Here, we show that treatment with tumor necrosis factor (TNF)–related …

Advances in experimental animal models of hepatocellular carcinoma

J Li, X Wang, M Ren, S He, Y Zhao - Cancer Medicine, 2023 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a common malignant tumor with insidious early
symptoms, easy metastasis, postoperative recurrence, poor drug efficacy, and a high drug …

[HTML][HTML] The roles of E3 ligases in Hepatocellular carcinoma

Z Yu, H Li, J Zhu, H Wang, X Jin - American journal of cancer …, 2022 - ncbi.nlm.nih.gov
Hepatocarcinogenesis is a complex multistep biological process involving genetic and
epigenetic alterations that are accompanied by activation of oncoproteins and inactivation of …