FreeSurfer‐based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other …

PG Sämann, JE Iglesias, B Gutman… - Human brain …, 2022 - Wiley Online Library
Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …

Medical image segmentation: a brief survey

A Elnakib, G Gimel'farb, JS Suri, A El-Baz - Multi Modality State-of-the-Art …, 2011 - Springer
Abstract Accurate segmentation of 2-D, 3-D, and 4-D medical images to isolate anatomical
objects of interest for analysis is essential in almost any computer-aided diagnosis system or …

A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology

JE Iglesias, R Insausti, G Lerma-Usabiaga… - Neuroimage, 2018 - Elsevier
The human thalamus is a brain structure that comprises numerous, highly specific nuclei.
Since these nuclei are known to have different functions and to be connected to different …

[HTML][HTML] A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI

JE Iglesias, JC Augustinack, K Nguyen, CM Player… - Neuroimage, 2015 - Elsevier
Automated analysis of MRI data of the subregions of the hippocampus requires
computational atlases built at a higher resolution than those that are typically used in current …

High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas

ZM Saygin, D Kliemann, JE Iglesias… - Neuroimage, 2017 - Elsevier
The amygdala is composed of multiple nuclei with unique functions and connections in the
limbic system and to the rest of the brain. However, standard in vivo neuroimaging tools to …

[HTML][HTML] Bayesian segmentation of brainstem structures in MRI

JE Iglesias, K Van Leemput, P Bhatt, C Casillas, S Dutt… - Neuroimage, 2015 - Elsevier
In this paper we present a method to segment four brainstem structures (midbrain, pons,
medulla oblongata and superior cerebellar peduncle) from 3D brain MRI scans. The …

A generative model for image segmentation based on label fusion

MR Sabuncu, BTT Yeo, K Van Leemput… - IEEE transactions on …, 2010 - ieeexplore.ieee.org
We propose a nonparametric, probabilistic model for the automatic segmentation of medical
images, given a training set of images and corresponding label maps. The resulting …

Automated segmentation of hippocampal subfields from ultra‐high resolution in vivo MRI

K Van Leemput, A Bakkour, T Benner, G Wiggins… - …, 2009 - Wiley Online Library
Recent developments in MRI data acquisition technology are starting to yield images that
show anatomical features of the hippocampal formation at an unprecedented level of detail …

Multi-contrast human neonatal brain atlas: application to normal neonate development analysis

K Oishi, S Mori, PK Donohue, T Ernst, L Anderson… - Neuroimage, 2011 - Elsevier
MRI is a sensitive method for detecting subtle anatomic abnormalities in the neonatal brain.
To optimize the usefulness for neonatal and pediatric care, systematic research, based on …

Bayesian longitudinal segmentation of hippocampal substructures in brain MRI using subject-specific atlases

JE Iglesias, K Van Leemput, J Augustinack, R Insausti… - Neuroimage, 2016 - Elsevier
The hippocampal formation is a complex, heterogeneous structure that consists of a number
of distinct, interacting subregions. Atrophy of these subregions is implied in a variety of …