Antimicrobial susceptibility testing of pathogens isolated from blood culture: a performance comparison of Accelerate Pheno™ and VITEK® 2 systems with the broth …

G De Angelis, B Posteraro, G Menchinelli… - Journal of …, 2019 - academic.oup.com
Objectives To compare the performance of the Accelerate Pheno™ system with that of the
conventional phenotypic VITEK® 2 system for rapid antimicrobial susceptibility testing (AST) …

[HTML][HTML] Treatment of multidrug-resistant Pseudomonas aeruginosa bacteremia using ceftolozane-tazobactam-based or colistin-based antibiotic regimens: a …

HA Hakeam, G Askar, K Al Sulaiman, R Mansour… - Journal of Infection and …, 2022 - Elsevier
Background Ceftolozane-tazobactam is an emerging‎ treatment for severe infections caused
by multidrug-resistant (MDR) Pseudomonas‎ aeruginosa. However, limited‎ data support its …

Antibiotic exposure profiles in trials comparing intensity of continuous renal replacement therapy

SM Jang, MP Pai, AR Shaw, BA Mueller - Critical Care Medicine, 2019 - journals.lww.com
Objectives: To determine whether the probability of target attainment over 72 hours of initial
therapy with beta-lactam (cefepime, ceftazidime, piperacillin/tazobactam) and carbapenem …

Management and outcome of bloodstream infections: a prospective survey in 121 French hospitals (SPA-BACT survey)

O Robineau, J Robert, C Rabaud… - Infection and Drug …, 2018 - Taylor & Francis
Background: Bloodstream infections (BSIs) are severe infections that can be community or
hospital acquired. Effects of time to appropriate treatment and impact of antimicrobial …

Predictive value of a quick pitt bacteremia score for prognosis of patients with bloodstream infection secondary to urinary tract infection: a retrospective cohort study

C Li, J Wang, Q Wang, B Liu, H Dang… - Infection and Drug …, 2022 - Taylor & Francis
Purpose To analyze the effect of a quick Pitt bacteremia score (qpitt) on the prognosis of
patients with bloodstream infection (BSI) secondary to urinary tract infection (UTI) and to …

Biomolecules capturing live bacteria from clinical samples

M Sorgenfrei, LM Hürlimann, MM Remy… - Trends in biochemical …, 2022 - cell.com
Rapid phenotypic antimicrobial susceptibility testing (AST) requires the enrichment of live
bacteria from patient samples, which is particularly challenging in the context of life …

[HTML][HTML] Ceftazidime-avibactam induced renal disorders: past and present

Y Shi, J Wu, W Mi, X Zhang, X Ren, C Shen… - Frontiers in …, 2024 - frontiersin.org
With the increasing prevalence of multidrug-resistant Gram-negative bacterial pathogens
worldwide, antimicrobial resistance has become a significant public health concern …

Early-and late-onset bloodstream infections in the intensive care unit: a retrospective 5-year study of patients at a University Hospital in China

J Xie, S Li, M Xue, C Yang, Y Huang… - The Journal of …, 2020 - academic.oup.com
Background Limited data are available regarding the current microbiological characteristics
of bloodstream infections (BSIs) in intensive care units (ICUs) in China. This retrospective …

Use of Transcriptional Signatures to Differentiate Pathogen-Specific and Treatment-Specific Host Responses in Patients With Bacterial Bloodstream Infections

JT Thaden, R Ahn, F Ruffin, DW Gjertson… - The Journal of …, 2024 - academic.oup.com
Background Clinical outcomes in bacterial bloodstream infections (BSIs) are influenced by
bacterial species, host immunity, and antibiotic therapy. The mechanisms by which such …

Effect of delayed antibiotic use on mortality outcomes in patients with sepsis or septic shock: A systematic review and meta-analysis

F Tang, H Yuan, X Li, L Qiao - International Immunopharmacology, 2024 - Elsevier
Background The use of antibiotics is essential in the treatment of sepsis and septic shock,
and delaying their administration may impact patient mortality outcomes. However, there is …