The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …

Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been related not only
to neurodevelopment and neuroprotection, but also to synapse regulation, learning, and …

Psychiatric disorders are one of the leading causes of disability worldwide and affect the
quality of life of both individuals and the society. The current understanding of these …

Several neurological diseases share pathological alterations, even though they differ in their
etiology. Neuroinflammation, altered brain glucose metabolism, oxidative stress …

The formation of correct synaptic structures and neuronal connections is paramount for
normal brain development and a functioning adult brain. The integrin family of cell adhesion …

Schizophrenia is a chronic and debilitating mental illness characterized by a broad range of
abnormal behaviors, including delusions and hallucinations, impaired cognitive function, as …

Protein expression abnormalities have been implicated in the pathophysiology of
schizophrenia, but the underlying cause of these changes is not known. We sought to …

Recent genome-wide association studies (GWAS) have identified multiple risk loci that show
strong associations with schizophrenia. However, pinpointing the potential causal genes at …

Arduous efforts have been made in the last three decades to elucidate the role of insulin in
the brain. A growing number of evidences show that insulin is involved in several …

Atypical antipsychotic drugs (AAPD s) have been suggested to be more effective in
improving cognitive impairment in schizophrenia than typical APD s, a conclusion supported …