Increasing diversity in connectomics with the Chinese Human Connectome Project

J Ge, G Yang, M Han, S Zhou, W Men, L Qin… - Nature …, 2023 - nature.com
Cultural differences and biological diversity play important roles in shaping human brain
structure and function. To date, most large-scale multimodal neuroimaging datasets have …

Perspectives on the future of dysmorphology

BD Solomon, MP Adam, CT Fong… - American Journal of …, 2023 - Wiley Online Library
The field of clinical genetics and genomics continues to evolve. In the past few decades,
milestones like the initial sequencing of the human genome, dramatic changes in …

Genotype Data and Derived Genetic Instruments of Adolescent Brain Cognitive Development Study® for Better Understanding of Human Brain Development

CC Fan, R Loughnan, S Wilson, JK Hewitt… - Behavior genetics, 2023 - Springer
The data release of Adolescent Brain Cognitive Development®(ABCD) Study represents an
extensive resource for investigating factors relating to child development and mental …

[HTML][HTML] Joint multi-ancestry and admixed GWAS reveals the complex genetics behind human cranial vault shape

S Goovaerts, H Hoskens, RJ Eller, N Herrick… - Nature …, 2023 - nature.com
The cranial vault in humans is highly variable, clinically relevant, and heritable, yet its
genetic architecture remains poorly understood. Here, we conduct a joint multi-ancestry and …

Forensic DNA phenotyping: Inferring phenotypic traits from crime scene DNA

P Dabas, S Jain, H Khajuria, BP Nayak - Journal of forensic and legal …, 2022 - Elsevier
Abstract Introduction Forensic DNA Phenotyping (FDP) has provided better understanding of
various phenotypic features (eg, height, skin colour, eye colour, structure and shape of scalp …

[PDF][PDF] GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development

AE Collier, SN Piekos, A Liu, JM Pattison, F Felix… - Iscience, 2023 - cell.com
Ectodermal dysplasias including skin abnormalities and cleft lip/palate result from improper
surface ectoderm (SE) patterning. However, the connection between SE gene regulatory …

[PDF][PDF] Genome-wide association study of hippocampal blood-oxygen-level-dependent-cerebral blood flow correlation in Chinese Han population

H Xue, X Xu, Z Yan, J Cheng, L Zhang, W Zhu, G Cui… - Iscience, 2023 - cell.com
Correlation between blood-oxygen-level-dependent (BOLD) and cerebral blood flow (CBF)
has been used as an index of neurovascular coupling. Hippocampal BOLD-CBF correlation …

Identification and validation of supervariants reveal novel loci associated with human white matter microstructure

S Wang, T Li, B Zhao, W Dai, Y Yao, C Li, T Li… - Genome …, 2024 - genome.cshlp.org
As an essential part of the central nervous system, white matter coordinates communications
between different brain regions and is related to a wide range of neurodegenerative and …

The pivotal role of the X-chromosome in the genetic architecture of the human brain

Z Jiang, PF Sullivan, T Li, B Zhao, X Wang, T Luo… - medRxiv, 2023 - medrxiv.org
Genes on the X-chromosome are extensively expressed in the human brain, resulting in
substantial influences on brain development, intellectual disability, and other brain-related …

The genetics of cortical organisation and development: a study of 2,347 neuroimaging phenotypes

V Warrier, EM Stauffer, QQ Huang, EM Wigdor… - bioRxiv, 2022 - biorxiv.org
Our understanding of the genetic architecture of the human cerebral cortex is limited both in
terms of the diversity of brain structural phenotypes and the anatomical granularity of their …