Imaging genomics reveals genetic architecture of the globular human braincase

B Molz, E Eising, G Alagoz, D Schijven, C Francks… - bioRxiv, 2024 - biorxiv.org
Compared with our fossil ancestors and Neandertal kin, modern humans have evolved a
distinctive skull shape, with a rounder braincase and more delicate face. Competing …

Regulatory Elements in SEM1–DLX5–DLX6 (7q21. 3) Locus Contribute to Genetic Control of Coronal Nonsyndromic Craniosynostosis and Bone Density-Related …

P Nicoletti, S Zafer, L Matok, I Irron, M Patrick… - Genetics in Medicine …, 2024 - Elsevier
Purpose The etiopathogenesis of coronal nonsyndromic craniosynostosis (cNCS), a
congenital condition defined by premature fusion of one or both coronal sutures, remains …

Whole exome sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes

S Ganesh, A Vemula, S Bhattacharjee, K Mathew… - Scientific Reports, 2022 - nature.com
Abstract Whole Exome Sequencing (WES) studies provide important insights into the
genetic architecture of serious mental illness (SMI). Genes that are central to the shared …

The Developmental Basis for Evolvability

B Hallgrímsson, JD Aponte, M Vidal-Garcia… - 2023 - direct.mit.edu
The origin of evolutionary developmental biology is often cast as a proj ect of synthesis
between evolutionary biology on the one hand and developmental biology on the other. In …

A genome-wide association study of Chinese and English language abilities in Hong Kong Chinese children

YP Lin, Y Shi, R Zhang, X Xue, S Rao, KFH Lui, DJ Pan… - medRxiv, 2022 - medrxiv.org
Background Reading and language skills are important and known to be heritable, and
dyslexia and developmental language disorder are commonly recognized learning …

Transforming the future of adolescent health: opportunities from the Adolescent Brain Cognitive Development Study

EA Hoffman, K LeBlanc, SRB Weiss… - Journal of Adolescent …, 2022 - jahonline.org
Adolescence is a period of dramatic expansion of the knowledge and skills critical for
transitioning into adulthood. Yet, there is much to learn about how adolescent experiences …

Face morphometric profiles of groups as early markers for certain diseases?

R Herrero, Y Martinez-Diaz… - … Journal of Oral and …, 2023 - organscigroup.us
Background: Face morphometry has been shown to work as a diagnosis tool in a set of
syndromes. Face similarities are usually indications of more complete genetic similarities …

Evolution and dysfunction of human cognitive and social traits: A transcriptional regulation perspective

R Zug, T Uller - Evolutionary Human Sciences, 2022 - cambridge.org
Evolutionary changes in brain and craniofacial development have endowed humans with
unique cognitive and social skills, but also predisposed us to debilitating disorders in which …

[PDF][PDF] BRAIN COMMUNICATIONS

R Bruffaerts, D Gors, AB Gallardo, M Vandenbulcke… - 2022 - air.unimi.it
Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers
of C9orf72 Page 1 BRAIN COMMUNICATIONS https://doi.org/10.1093/braincomms/fcac182 …

[引用][C] MOLECULAR DIAGNOSTICS IN AUTISM SPECTRUM DISORDER: NEXT GENERATION SEQUENCING AND FACIAL PHENOTYPING IN MEDICAL …

Y Sleyp - 2022