Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

People with damage to the orbitofrontal cortex (OFC) have specific problems making
decisions, whereas their other cognitive functions are spared. Neurophysiological studies …

The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …

Situations in which rewards are unexpectedly obtained or withheld represent opportunities
for new learning. Often, this learning includes identifying cues that predict reward …

Happiness and other emotions spread between people in direct contact, but it is unclear
whether massive online social networks also contribute to this spread. Here, we elaborate a …

Associative learning is driven by prediction errors. Dopamine transients correlate with these
errors, which current interpretations limit to endowing cues with a scalar quantity reflecting …

The orbitofrontal cortex (OFC) has long been associated with the flexible control of behavior
and concepts such as behavioral inhibition, self-control, and emotional regulation. These …

The prefrontal cortex makes up almost a quarter of the human brain, and it expanded
dramatically during primate evolution. The Neurobiology of the Prefrontal Cortex presents a …

Midbrain dopamine neurons have been proposed to signal prediction errors as defined in
model-free reinforcement learning algorithms. While these algorithms have been extremely …

Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One
holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory …