Synaptic dysfunction and plasticity in amyotrophic lateral sclerosis

R Gulino - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent evidence has supported the hypothesis that amyotrophic lateral sclerosis (ALS) is a
multi-step disease, as the onset of symptoms occurs after sequential exposure to a defined …

Piezoelectric composite hydrogel with wireless electrical stimulation enhances motor functional recovery of spinal cord injury

Z Li, G Li, X Wang, Z Zhao - Journal of Materials Science & Technology, 2024 - Elsevier
Electrical stimulation (ES) can restore motor function after spinal cord injury (SCI). However,
traditional intraspinal ES has many disadvantages, such as the need for a complex circuitry …

Combined transcutaneous electrical spinal cord stimulation and task-specific rehabilitation improves trunk and sitting functions in people with chronic tetraplegia

NS Tharu, M Alam, YT Ling, AYL Wong, YP Zheng - Biomedicines, 2022 - mdpi.com
The aim of this study was to examine the effects of transcutaneous electrical spinal cord
stimulation (TSCS) and conventional task-specific rehabilitation (TSR) on trunk control and …

Gut microbiome and neurosurgery: Implications for treatment

J Willman, M Willman, R Reddy, A Fusco… - Clinical and …, 2022 - Wiley Online Library
Introduction The aim of this review is to summarize the current understanding of the gut‐
brain axis (GBA), its impact on neurosurgery, and its implications for future treatment …

Recalibration of neuromodulation parameters in neural implants with adaptive Bayesian optimization

G Aiello, G Valle, S Raspopovic - Journal of Neural Engineering, 2023 - iopscience.iop.org
Objective. Neuromodulation technology holds promise for treating conditions where
physiological mechanisms of neural activity have been affected. To make treatments efficient …

Spinal cord stimulation prevents autonomic dysreflexia in individuals with spinal cord injury: a case series

S Samejima, C Shackleton, RN Malik, K Cao… - Journal of Clinical …, 2023 - mdpi.com
Spinal cord injury (SCI) results in severe cardiovascular dysfunction due to the disruption of
supraspinal control. Autonomic dysreflexia (AD), an uncontrolled rise in blood pressure in …

Effects of non-invasive spinal cord stimulation on lower urinary tract, bowel, and sexual functions in individuals with chronic motor-complete spinal cord injury: Protocol …

S Samejima, C Shackleton, L McCracken, RN Malik… - Plos one, 2022 - journals.plos.org
Introduction Electrical spinal cord neuromodulation has emerged as a leading intervention
for restoring autonomic functions, such as blood pressure, lower urinary tract (LUT), bowel …

[HTML][HTML] Combining spinal neuromodulation and activity based neurorehabilitation therapy improves sensorimotor function in cerebral palsy

R Sachdeva, K Girshin, Y Shirkhani, P Gad… - Frontiers in …, 2023 - frontiersin.org
Motor dysfunction in individuals with cerebral palsy (CP) such as the inability to initiate
voluntary movements, walking with compensatory movement patterns, and debilitating …

REPORT-SCS: minimum reporting standards for spinal cord stimulation studies in spinal cord injury

RN Malik, S Samejima, C Shackleton… - Journal of neural …, 2024 - iopscience.iop.org
Objective. Electrical spinal cord stimulation (SCS) has emerged as a promising therapy for
recovery of motor and autonomic dysfunctions following spinal cord injury (SCI). Despite the …

Motor-targeted spinal stimulation promotes concurrent rebalancing of pathologic nociceptive transmission in chronic spinal cord injury

MF Bandres, JL Gomes, JG McPherson - bioRxiv, 2023 - biorxiv.org
Electrical stimulation of spinal networks below a spinal cord injury (SCI) is a promising
approach to restore functions compromised by inadequate excitatory neural drive. The most …