Background The gut microbiome is closely related to gastrointestinal (GI) cancer, but the
causality of gut microbiome with GI cancer has yet to be fully established. We conducted this …

Background While targeted systemic inflammatory modulators show promise in preventing
chronic kidney disease (CKD) progression, the causal link between specific inflammatory …

Background Increasing evidence from observational studies and clinical experimentation
has indicated a link between the gut microbiotas (GMs) and polycystic ovary syndrome …

Objective The positive association between rheumatoid arthritis (RA) and osteoporosis has
been reported in previous observational studies, but the causal relationship remains …

Objective: According to the 2020 data from the World Health Organization (WHO), cancers
stand as one of the foremost contributors to global mortality. Revealing novel cancer risk …

Regardless of the currently proposed best medical treatment for heart failure patients, the
morbidity and mortality rates remain high. This is due to several reasons, including the …

Background Despite establishing an association between gut microbiota and
spondyloarthritis (SpA) subtypes, the causal relationship between them remains unclear …

Background Targeting the gut microbiota may become a new therapeutic to prevent and
treat sepsis. Nonetheless, the causal relationship between specific intestinal flora and …

The role of the gut microbiota in modulating the risk of respiratory infections has garnered
increasing attention. However, conventional clinical trials have faced challenges in …

Background Recent studies have suggested a relationship between gut microbiota and non-
alcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH). However, the …