G Nocturne, X Mariette - Nature Reviews Rheumatology, 2018 - nature.com
Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …
G Nocturne, X Mariette - Nature Reviews Rheumatology, 2013 - nature.com
Primary Sjögren's syndrome (pSS) is a prototypic autoimmune disorder, management of which has long suffered from a lack of knowledge of the underlying pathophysiological …
LE Muñoz, K Lauber, M Schiller, AA Manfredi… - Nature Reviews …, 2010 - nature.com
The inefficient clearance of dying cells can result in the accumulation of apoptotic cell remnants. This occurrence is considered an intrinsic defect that can cause the permanent …
Sjogren's syndrome is characterized by the presence of a plethora of autoantibodies (Table 1). We herein review major recent development in autoantibodies associated with Sjogren …
Systemic Lupus Erythematosus (SLE) is characterized by a wide spectrum of auto- antibodies which recognize several cellular components. The production of these self …
The critical function of the immune system is to discriminate self from non-self. Tolerance against self-antigens is a highly regulated process and, in order to maintain it, the immune …
T Hung, GA Pratt, B Sundararaman, MJ Townsend… - Science, 2015 - science.org
Autoantibodies target the RNA binding protein Ro60 in systemic lupus erythematosus (SLE) and Sjögren's syndrome. However, it is unclear whether Ro60 and its associated RNAs …
AM Ciobanu, AE Dumitru, N Gica, R Botezatu… - Diagnostics, 2020 - mdpi.com
Maternal passage of immunoglobulin G (IgG) is an important passive mechanism for protecting the infant while the neonatal immune system is still immature and ineffective. IgG …
H Suryawanshi, R Clancy, P Morozov… - Cardiovascular …, 2020 - academic.oup.com
Aims Investigating human heart development and applying this to deviations resulting in disease is incomplete without molecular characterization of the cell types required for …