[HTML][HTML] Structure, function, and genetics of lipoprotein (a)

K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

[HTML][HTML] Lipoprotein (a) measurements for clinical application

SM Marcovina, JJ Albers - Journal of lipid research, 2016 - ASBMB
The high degree of size heterogeneity of apo (a), the distinct protein component of
lipoprotein (a)[Lp (a)], renders the development and selection of specific antibodies directed …

Lepodisiran, an extended-duration short interfering RNA targeting lipoprotein (a): a randomized dose-ascending clinical trial

SE Nissen, H Linnebjerg, X Shen, K Wolski, X Ma… - Jama, 2023 - jamanetwork.com
Importance Epidemiological and genetic data have implicated lipoprotein (a) as a potentially
modifiable risk factor for atherosclerotic disease and aortic stenosis, but there are no …

Use of Lipoprotein (a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association

DP Wilson, TA Jacobson, PH Jones… - Journal of clinical …, 2019 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a well-recognized, independent risk factor for
atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in …

Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Lipoprotein (a) levels and the risk of myocardial infarction among 7 ethnic groups

G Paré, A Çaku, M McQueen, SS Anand, E Enas… - Circulation, 2019 - Am Heart Assoc
Background: Lipoprotein (a)[Lp (a)] levels predict the risk of myocardial infarction (MI) in
populations of European ancestry; however, few data are available for other ethnic groups …

[HTML][HTML] Atherosclerotic cardiovascular disease risk assessment: An American Society for Preventive Cardiology clinical practice statement

ND Wong, MJ Budoff, K Ferdinand, IM Graham… - American journal of …, 2022 - Elsevier
Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of …

PS Jellinger, Y Handelsman, PD Rosenblit… - Endocrine Practice, 2017 - Elsevier
Objective The development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology …

Lipoprotein (a) as a cardiovascular risk factor: current status

BG Nordestgaard, MJ Chapman, K Ray… - European heart …, 2010 - academic.oup.com
Aims The aims of the study were, first, to critically evaluate lipoprotein (a)[Lp (a)] as a
cardiovascular risk factor and, second, to advise on screening for elevated plasma Lp (a), on …

Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association

LB Goldstein, CD Bushnell, RJ Adams, LJ Appel… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …