How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review

AM Freeman, K Petrilli, R Lees, C Hindocha… - Neuroscience & …, 2019 - Elsevier
The recent liberalisation of cannabis regulation has increased public and scientific debate
about its potential benefits and risks. A key focus has been the extent to which cannabidiol …

Effects of cannabis on the adolescent brain

J Jacobus, SF Tapert - Current pharmaceutical design, 2014 - ingentaconnect.com
This article reviews neuroimaging, neurocognitive, and preclinical findings on the effects of
cannabis on the adolescent brain. Marijuana is the second most widely used intoxicant in …

Traditional marijuana, high‐potency cannabis and synthetic cannabinoids: increasing risk for psychosis

RM Murray, H Quigley, D Quattrone… - World …, 2016 - Wiley Online Library
Epidemiological evidence demonstrates that cannabis use is associated with an increased
risk of psychotic outcomes, and confirms a dose‐response relationship between the level of …

Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus

AV Stempel, A Stumpf, HY Zhang, T Özdoğan… - Neuron, 2016 - cell.com
Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …

Evidence on the acute and residual neurocognitive effects of cannabis use in adolescents and adults: A systematic meta‐review of meta‐analyses

L Dellazizzo, S Potvin, S Giguère, A Dumais - Addiction, 2022 - Wiley Online Library
Background Cannabis is among the most consumed psychoactive substances world‐wide.
Considering changing policy trends regarding the substance, it is crucial to understand more …

Non‐motor symptoms in Parkinson's disease are reduced by nabilone

M Peball, F Krismer, HG Knaus… - Annals of …, 2020 - Wiley Online Library
Objective The objective of this study was to assess the efficacy and safety of nabilone, a
synthetic tetrahydrocannabinol analogue, as a treatment for non‐motor symptoms (NMS) in …

Cannabis use and the development of tolerance: a systematic review of human evidence

M Colizzi, S Bhattacharyya - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
Previous studies have reported conflicting results in terms of acute effects of cannabis in
man. Independently of other factors, such discrepancy may be attributable to the different …

[HTML][HTML] The short-term and long-term effects of cannabis on cognition: recent advances in the field

E Kroon, L Kuhns, J Cousijn - Current Opinion in Psychology, 2021 - Elsevier
The aim of this review is to discuss the most recent evidence for the short-term and long-term
effects of cannabis on cognition. The evidence that cannabis intoxication is associated with …

Heavy cannabis use, dependence and the brain: a clinical perspective

E Kroon, L Kuhns, E Hoch, J Cousijn - Addiction, 2020 - Wiley Online Library
Aims To summarize and evaluate our knowledge of the relationship between heavy
cannabis use, cannabis use disorder (CUD) and the brain. Methods Narrative review of …

[HTML][HTML] Safety and toxicology of cannabinoids

J Sachs, E McGlade, D Yurgelun-Todd - Neurotherapeutics, 2015 - Elsevier
There is extensive research on the safety, toxicology, potency, and therapeutic potential of
cannabis. However, uncertainty remains facilitating continued debate on medical and …