Lupus nephritis

HJ Anders, R Saxena, M Zhao, I Parodis… - Nature reviews Disease …, 2020 - nature.com
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

Hepatitis B virus infection

C Trépo, HLY Chan, A Lok - The Lancet, 2014 - thelancet.com
Hepatitis B virus infection is a major public health problem worldwide; roughly 30% of the
world's population show serological evidence of current or past infection. Hepatitis B virus is …

[PDF][PDF] The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe

ZM Younossi, D Blissett, R Blissett, L Henry… - …, 2016 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease. There is
uncertainty around the economic burden of NAFLD. We constructed a steady‐state …

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

SK Sarin, M Kumar, GK Lau, Z Abbas, HLY Chan… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double …

M Buti, E Gane, WK Seto, HLY Chan… - The lancet …, 2016 - thelancet.com
Background The novel prodrug tenofovir alafenamide delivers the nucleotide reverse
transcriptase inhibitor tenofovir to target cells more efficiently at a lower dose than tenofovir …

[PDF][PDF] Antiviral therapy for chronic hepatitis B viral infection in adults: a systematic review and meta‐analysis

ASF Lok, BJ McMahon, RS Brown Jr, JB Wong… - …, 2016 - Wiley Online Library
Chronic hepatitis B viral (HBV) infection remains a significant global health problem.
Evidence‐based guidelines are needed to help providers determine when treatment should …

Current trend in antiviral therapy for chronic hepatitis B

RN Chien, YF Liaw - Viruses, 2022 - mdpi.com
Since active hepatitis B virus (HBV) replication is the key driver of hepatic necroinflammation
and disease progression, the treatment aim of chronic hepatitis B (CHB) is to suppress HBV …

Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of HBeAg-positive chronic hepatitis B virus infection: a randomised, double-blind, phase 3 …

HLY Chan, S Fung, WK Seto, WL Chuang… - The lancet …, 2016 - thelancet.com
Background Tenofovir alafenamide is a novel prodrug formulated to deliver the active
metabolite to target cells more efficiently than tenofovir disoproxil fumarate at a lower dose …

American Gastroenterological Association Institute technical review on prevention and treatment of hepatitis B virus reactivation during immunosuppressive drug …

RP Perrillo, R Gish, YT Falck-Ytter - Gastroenterology, 2015 - gastrojournal.org
This article has an accompanying continuing medical education activity on page e16.
Learning Objective: Upon completion of the CME activity, successful learners will be able to …

[HTML][HTML] Risk of hepatocellular carcinoma in chronic hepatitis B: assessment and modification with current antiviral therapy

GV Papatheodoridis, HLY Chan, BE Hansen… - Journal of …, 2015 - Elsevier
In the treatment of chronic hepatitis B (CHB), the ultimate goal is preventing hepatitis B virus
(HBV)-associated liver disease, including hepatocellular carcinoma (HCC). Recently …