Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide
(LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found …

Neuronal loss is one of the striking causes of various central nervous system disorders,
including major neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …

Background Increasing evidence suggests that patients with Parkinson's disease (PD)
present with peripheral autonomic dysfunction (AutD) that even precedes motor deficits …

Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
characterized by motor and non-motor disturbances as a result of a complex and not fully …

Human prion protein and prion-like protein misfolding are widely recognized as playing a
causal role in many neurodegenerative diseases. Based on in vitro and in vivo experimental …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Parkinson's disease (PD) is a complicated neurodegenerative disease, of which
gastrointestinal disturbance appears prior to motor symptoms. Numerous studies have shed …